Pediatric Neurology
Volume 24, Issue 4 , Pages 303-305, April 2001

Acute disseminated encephalomyelitis in autoimmune hemolytic anemia

  • Tang-Her Jaing, MD

      Affiliations

    • Divisions of Hematology and Oncology, Chang Gung Children’s Hospital, Taoyuan, Taiwan
    • Corresponding Author InformationCommunications should be addressed to: Dr. Jaing; Division of Hematology and Oncology, Department of Medicine; Chang Gung Children’s Hospital; 5 Fu-Shin Street, Kwei-Shan 333, Taoyuan, Taiwan
    • ,
  • Kuang-Lin Lin, MD

      Affiliations

    • Division of Neurology, Chang Gung Children’s Hospital, Taoyuan, Taiwan
    • ,
  • Cheng-Hsun Chiu, MD, PhD

      Affiliations

    • Division of Infectious Diseases, Chang Gung Children’s Hospital, Taoyuan, Taiwan
    • ,
  • Wan-Chak Lo, MD

      Affiliations

    • Department of Medicine, Chang Gung Children’s Hospital, Taoyuan, Taiwan
    • ,
  • Paul-Lee Wu, MD

      Affiliations

    • Department of Radiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan

Received 20 July 2000; accepted 5 December 2000.

Abstract 

A 16-year-old female with chronic autoimmune hemolytic anemia is presented. She was diagnosed with acute disseminated encephalomyelitis by clinical findings and magnetic resonance imaging (MRI), and the condition occurred after a systemic infection with Cryptococcus neoformans. Intravenous immunoglobulin therapy remarkably improved the patient’s neurologic deficit and resolved abnormalities evidenced on MRI. To our knowledge, this report is the first of a pediatric patient with autoimmune hemolytic anemia complicated by acute disseminated encephalomyelitis that developed after an apparently successful treatment of cryptococcal meningitis.

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PII: S0887-8994(00)00267-8

Pediatric Neurology
Volume 24, Issue 4 , Pages 303-305, April 2001

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