Pediatric Neurology
Volume 25, Issue 1 , Pages 67-70 , July 2001

Mycoplasma pneumoniae infection, meningoencephalitis, and hemophagocytosis

  • Leslie A Bruch, MD

      Affiliations

    • Department of Neuropathology; University of Nebraska Medical Center; Omaha, NE, USA
    • ,
  • Rosalind J Jefferson, MBBS, PhD

      Affiliations

    • Department of Pediatrics; John Radcliffe Hospital; Oxford, United Kingdom
    • ,
  • Michael G Pike, MD

      Affiliations

    • Department of Pediatrics; John Radcliffe Hospital; Oxford, United Kingdom
    • ,
  • Stephen J Gould, MBBS

      Affiliations

    • Department of Pathology; Womens Centre; John Radcliffe Hospital; Oxford, United Kingdom
    • ,
  • Waney Squier, MBchB

      Affiliations

    • Department of Neuropathology; Radcliffe Infirmary; Oxford, United Kingdom
    • Corresponding Author InformationCommunications should be addressed to: Dr. Squier; Department of Neuropathology; Radcliffe Infirmary; Oxford, OX2 6HE, UK

Received 2 October 2000 ,Accepted 6 March 2001.

References 

  1. Lehtokoski-Lehtiniemi E, Koskiniemi M. Mycoplasma pneumoniae encephalitis (A severe entity in children). Pediatr Infect Dis J. 1989;8:651–653
  2. Rautoneu J, Koskiniemi M, Vaheri A. Prognostic factors in childhood acute encephalitis. Pediatr Infect Dis J. 1991;10:441–446
  3. Koskiniemi M. CNS manifestations associated with Mycoplasma pneumoniae infections (Summary of cases at the University of Helsinki and review). Clin Infect Dis. 1993;17:S52–S57
  4. Gill K, Marrie TJ. Hemophagocytosis secondary to Mycoplasma pneumoniae infection. Am J Med 1987;82:688–70.
  5. Abramovitz P, Schvartzman P, Harel D, Lis I, Naot Y. Direct invasion of the central nervous system by Mycoplasma pneumoniae (A report of two cases). J Infect Dis. 1987;155:482–487
  6. Yesnick L. Central nervous system complications of primary atypical pneumonia. Arch Intern Med. 1956;97:93–98
  7. Fisher RS, Clark AW, Wolinsky JS, Parhad IM, Moses H, Mardinay MR. Postinfectious leukoencephalitis complicating Mycoplasma pneumoniae infection. Arch Neurol. 1983;40:109–113
  8. Behan PO, Feldman RG, Segerra JM, Draper IT. Neurological aspects of Mycoplasma infection. Acta Neurol Scand. 1986;74:314–322
  9. Risdall RJ, McKenna RW, Nesbit ME, et al.  Virus-associated hemophagocytic syndrome (A benign histiocytic proliferation distinct from malignant histiocytosis). Cancer. 1979;44:993–1002
  10. Wong KF, Chen JKC. Hemophagocytic disorders - A review. Hematol Rev. 1991;5:5–37
  11. Tsuda H, Maeda Y, Nakagawa K, McDermid G, Gray JA, Parker AC. Parvovirus B19-associated haemophagocytic syndrome with prominent neutrophilia. Br J Haematol. 1994;86:413–414
  12. Shirono K, Tsuda H. Virus-associated haemophagocytic syndrome in previously healthy adults. Eur J Haematol. 1995;55:240–244
  13. Watson HG, Goulden NJ, Manson LM, et al.  Virus-associated haemophagocytic syndrome (Further evidence for a T-cell mediated disorder). Br J Haematol. 1994;86:213–215
  14. Imashuku S, Hibi S. Cytokines in haemophagocytic syndrome. Br J Haematol. 1991;77:438–440
  15. Tsuda H, Shirono K. A possible role of macrophage colony stimulating factor (M-CSF) in the development of haemophagocytic syndrome. Eur J Haematol. 1995;54:197

PII: S0887-8994(01)00274-0

Pediatric Neurology
Volume 25, Issue 1 , Pages 67-70 , July 2001

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