Pediatric Neurology
Volume 25, Issue 2 , Pages 166-169 , August 2001

Cranial MRI changes may precede symptoms in Hallervorden-Spatz syndrome

  • Susan J. Hayflick, MD

      Affiliations

    • Department of Molecular and Medical Genetics; Oregon Health Sciences University; Portland, OR, USA
    • Department of Pediatrics; Oregon Health Sciences University; Portland, OR, USA
    • Department of Neurology; Oregon Health Sciences University; Portland, OR, USA
    • Corresponding Author InformationCommunications should be addressed to: Dr. Hayflick; Oregon Health and Science University; Mail Code L103a; 3181 SW Sam Jackson Park Rd.; Portland, OR 97201
    • ,
  • Johann M. Penzien, MD

      Affiliations

    • Division of Neuropediatrics; Zentralklinikum; Augsburg, Germany
    • ,
  • Wolfgang Michl, MD

      Affiliations

    • Division of Pediatric Radiology; Zentralklinikum; Augsburg, Germany
    • ,
  • Uzma M. Sharif, MD

      Affiliations

    • Department of Neurology; Tufts University School of Medicine; New England Medical Center; Boston, Massachusetts, USA
    • ,
  • N.Paul Rosman, MD

      Affiliations

    • Department of Neurology; Tufts University School of Medicine; New England Medical Center; Boston, Massachusetts, USA
    • Department of Pediatrics; Tufts University School of Medicine; New England Medical Center; Boston, Massachusetts, USA
    • ,
  • Patricia G. Wheeler, MD

      Affiliations

    • Department of Pediatrics; Tufts University School of Medicine; New England Medical Center; Boston, Massachusetts, USA

Received 20 December 2000 ,Accepted 3 April 2001.

References 

  1. Dooling EC, Schoene WC, Richardson EP. Hallervorden-Spatz syndrome. Arch Neurol. 1974;30:70–83
  2. Swaiman KF. Hallervorden-Spatz syndrome and brain iron metabolism. Arch Neurol. 1991;48:1285–1293
  3. Tanfani G, Mascalchi M, Dal Pozzo GC, Taverni N, Saia A, Trevisan C. MR imaging in a case of Hallervorden-Spatz disease. J Comput Assist Tomogr. 1987;11:1057–1058
  4. Mutoh K, Okuno T, Ito M, et al.  MR imaging of a group I case of Hallervorden-Spatz disease. J Comput Assist Tomogr. 1988;12:851–853
  5. Sethi KD, Adams RJ, Loring DW, el Gammal T. Hallervorden-Spatz syndrome (Clinical and magnetic resonance imaging correlations). Ann Neurol. 1988;24:692–694
  6. Angelini L, Nardocci N, Rumi V, Zorzi C, Strada L, Savoiardo M. Hallervorden-Spatz disease (Clinical and MRI study of 11 cases diagnosed in life). J Neurol. 1992;239:417–425
  7. Taylor TD, Litt M, Kramer P, et al.  Homozygosity mapping of Hallervorden-Spatz syndrome to chromosome 20p12.3-p13. Nat Genet. 1996;14:479–481

PII: S0887-8994(01)00296-X

Pediatric Neurology
Volume 25, Issue 2 , Pages 166-169 , August 2001

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