Pediatric Neurology
Volume 26, Issue 1 , Pages 18-25, January 2002

Pediatric tumefactive demyelination: case series and review of the literature

  • Laura C McAdam, MSc, MD

      Affiliations

    • Department of Pediatrics, Foothills Hospital, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Susan I Blaser, MD

      Affiliations

    • Department of Diagnostic Imaging, University of Toronto; The Hospital for Sick Children, Toronto, Ontario, Canada
    • ,
  • Brenda L Banwell, MD

      Affiliations

    • Corresponding Author InformationCommunications should be addressed to: Dr. Banwell, Department of Pediatrics (Neurology); 6th Floor Gerrard Wing; University of Toronto; The Hospital for Sick Children; 555 University Avenue; Toronto, Ontario, Canada M5G 1X9
    • Department of Pediatrics (Neurology) University of Toronto; The Hospital for Sick Children, Toronto, Ontario, Canada

Received 16 November 2000; accepted 6 June 2001.

Abstract 

Tumefactive demyelinating lesions may be misdiagnosed as brain neoplasms or abscesses. In this paper, we present four cases of pediatric tumefactive demyelination. Twelve cases of pediatric tumefactive demyelination previously reported in the English literature are also summarized. We describe the neuroimaging characteristics and clinical presentation of tumefactive demyelination and how these features may be used in differentiating demyelination from other mass lesions.

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PII: S0887-8994(01)00322-8

Pediatric Neurology
Volume 26, Issue 1 , Pages 18-25, January 2002

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