Pediatric Neurology
Volume 26, Issue 3 , Pages 192-195 , March 2002

Increased frequency of interleukin-1β (−511) allele 2 in febrile seizures

  • Miia Virta, MS

      Affiliations

    • Department of Microbiology and Immunology; University of Tampere Medical School and Tampere University Hospital; Tampere, Finland
    • ,
  • Mikko Hurme, MD

      Affiliations

    • Department of Microbiology and Immunology; University of Tampere Medical School and Tampere University Hospital; Tampere, Finland
    • ,
  • Merja Helminen, MD

      Affiliations

    • Corresponding Author InformationCommunications should be addressed to: Dr. Helminen; Department of Pediatrics; Tampere University Hospital; P.O. Box 2000; FIN-33521, Tampere, Finland
    • Department of Pediatrics, Tampere University Hospital, Tampere, Finland

Received 22 May 2001 ,Accepted 20 September 2001.

References 

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  2. Johnson WG, Kugler SL, Stenroos ES, et al.  Pedigree analysis in families with febrile seizures. Am J Med Genet. 1996;61:345–352
  3. Peiffer A, Thompson J, Charlier C, et al.  A locus for febrile seizures (FEB3) maps to chromosome 2q23–24. Ann Neurol. 1999;46:671–678
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  14. Pociot F, Mølvig J, Wogensen L, Worsaae H, Nerup J. A TaqI polymorphism in the human interleukin-1β (IL-1β) gene correlates with IL-1β secretion in vitro. Eur J Clin Invest. 1992;22:396–402
  15. di Giovine FS, Takhsh E, Blakemore AIF, Duff GW. Single base polymorphism at −511 in the human interleukin- 1β gene (IL1β). Hum Mol Genet. 1992;1:450
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Pediatric Neurology
Volume 26, Issue 3 , Pages 192-195 , March 2002

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