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Pediatric Neurology
Volume 26, Issue 3
, Pages 181-185
, March 2002
Pyridoxine-dependent seizures: findings from recent studies pose new questions
References
- . Pyridoxine dependency (Report of a case of intractable convulsions in an infant controlled by pyridoxine). Pediatrics. 1954;13:140–145
- . Epidemiology of pyridoxine dependent and pyridoxine responsive seizures in the UK. Arch Dis Child. 1999;81:431–433
- . Pyridoxine dependency (An update). Dev Med Child Neurol. 1997;39:63–65
- . Current perspectives on pyridoxine-dependent seizures. J Pediatr. 1998;132:919–923
- . Pyridoxine-dependent seizures, clinical and therapeutic aspects. Eur J Pediatr. 1991;150:452–455
- . Pyridoxine-dependent and pyridoxine-responsive seizures. Dev Med Child Neurol. 2001;43:416–420
- . Pyridoxine dependent seizures—a wider clinical spectrum. Arch Dis Child. 1983;58:415–418
- . Atypical presentations of pyridoxine-dependent seizures (A treatable cause of intractable epilepsy in infants). Ann Neurol. 1985;17:117–120
- . Pyridoxine-dependent seizures requiring high doses of pyridoxine for control. Am J Dis Child. 1979;133:963–965
- . Postneonatal vitamin B6-dependent epilepsy. Pediatrics. 1992;90:221–223
-
.
Late-onset pyridoxine-dependent seizures (Report of two cases).
Acta Paediatr Sin. 1995;36:434–437
- . Pyridoxine-dependent epilepsy (The need for repeated pyridoxine trials and the risk of severe electrocerebral suppression with intravenous pyridoxine infusion). J Child Neurol. 1996;11:422–424
- . Pyridoxine-dependent seizures responding to extremely low-dose pyridoxine. Dev Med Child Neurol. 2001;43:413–415
- . Glutamate decarboxylase is not genetically linked to pyridoxine-dependent seizures. Neurology. 2000;55:309–311
- A gene for pyridoxine-dependent epilepsy maps to chromosome 5q31. Am J Hum Genet. 2000;67:991–993
- Mutation and polymorphic marker analyses of 65K- and 67K-glutamate decarboxylase genes in two families with pyridoxine-dependent epilepsy. J Hum Genet. 1998;43:128–131
- . Glutamate in pyridoxine-dependent epilepsy (Neurotoxic glutamate concentration in the cerebrospinal fluid and its normalization by pyridoxine). Pediatrics. 1994;94:318–321
- . Reduced GABA synthesis in pyridoxine-dependent seizures. Lancet. 1994;343:1133–1134
- . Low level of GABA in CSF in vitamin B6-dependent seizures. Dev Med Child Neurol. 1991;33:749–750
- . Disturbance of GABA metabolism in pyridoxine-dependent seizures. Neuropediatrics. 1992;23:257–259
- A subtype of pyridoxine-dependent epilepsy with normal CSF glutamate concentration. J Inherit Metab Dis. 1998;21:431–432
- . Pyridoxine-dependent seizures (Demographic, clinical, MRI and psychometric features, and effect of dose on intelligence quotient). Dev Med Child Neurol. 1996;38:998–1006
- . Global brain dysfunction in an infant with pyridoxine dependency (Evaluation with EEG, evoked potentials, MRI, and PET). Neurology. 1996;47:824–826
- . Pyridoxine-dependent seizures (Report of a case with atypical clinical features and abnormal MRI scans). J Child Neurol. 1992;7:24–28
- Pyridoxine-dependent seizures associated with white matter abnormalities. Neuropediatrics. 1994;25:259–261
- . Longitudinal MRI findings in pyridoxine-dependent seizures. Neurology. 1998;51:74–78
- . Pyridoxine-dependent epilepsy (EEG investigation and long-term follow-up). Electroencephalogr Clin Neurophysiol. 1991;78:215–221
-
.
Pyridoxine dependent epilepsy (A suggestive electroclinical pattern).
Arch Dis Child Fetal Neonatal Educ. 1999;81:F125–F129
- . Familial intrauterine convulsions in pyridoxine dependency. Arch Dis Child. 1967;42:201–207
- . Pyridoxine for neonatal seizures (An unexpected danger). Dev Med Child Neurol. 1985;27:369–382
- . Vitamin B6 and valproic acid in treatment of infantile spasms. Pediatr Neurol. 1991;7:91–96
- . Treatment of infantile spasms with high-dosage vitamin B6. Epilepsia. 1993;34:757–763
- . Long-term follow-up of vitamin B6-responsive West syndrome. Pediatr Neurol. 2000;23:202–206
- . ACTH therapy for infantile spasms (A combination therapy with high-dose pyridoxal phosphate and low-dose ACTH). Epilepsia. 1998;39(Suppl 5):42–45
- Randomized, controlled trial of high-dose intravenous pyridoxine in the treatment of recurrent seizures in children. Pediatr Neurol. 1997;17:54–57
- . Effect of pyridoxine treatment in children with epilepsy. Acta Soc Med Ups. 1968;73:35–43
- . A 15-year follow-up of a boy with pyridoxine (vitamin B6)-dependent seizures with autism, breath holding, and severe mental retardation. J Child Neurol. 2000;15:763–765
- . Pyridoxine dependent epilepsy with iatrogenic sensory neuronopathy. Can J Neurol Sci. 1995;22:50–51
- . Long-term follow-up of an individual with vitamin B6-dependent seizures. Dev Med Child Neurol. 1999;41:203–206
- . Neonatal seizures after pyridoxine use. [letter] Lancet. 1999;354:2082–2083
- . Vitamin B6-dependency and infantile convulsions. Pediatrics. 1960;26:62–74
- . Vitamin B6-dependent seizures (Pathology and chemical findings in brain). Neurology. 1978;28:47–54
- . CSF glutamate/GABA concentrations in pyridoxine-dependent seizures (Etiology of pyridoxine-dependent seizures and the mechanisms of pyridoxine action in seizure control). Brain Dev. 2001;23:24–29
- . Pyridoxine-responsive West syndrome and gamma-aminobutyric acid. Eur J Pediatr. 1997;156:158–159
-
.
Vitamin B6 safety issues.
Ann NY Acad Sci. 1990;585:321–330
- . Anticonvulsant activity of muscimol and gamma-aminobutyric acid against pyridoxal phosphate-induced seizures. J Neurochem. 1981;36:251–257
- . Proconvulsant effects induced by pyridoxine in young rats. Epilepsy Res. 1998;29:259–264
- . A paradoxical rise of neonatal seizures after treatment with vitamin B6. Eur J Paediatr Neurol. 1998;2:319–322
-
.
A new method to detect point mutations in the gene for glutamic acid decarboxylase in patients with pyridoxine-dependent seizures.
[abstract]
Ann Neurol. 1987;22:446–447
- . Pipecolic acid elevation in plasma and cerebrospinal fluid of two patients with pyridoxine-dependent epilepsy. Ann Neurol. 2000;48:121–125
- . Influence of pipecolic acid on the release and uptake of [3H]-GABA from brain slices of mouse cerebral cortex. Neurochem Res. 1989;14:405–408
- . Mutations in a new gene encoding a thiamine transporter cause thiamine-responsive megaloblastic anaemia syndrome. Nat Genet. 1999;22:309–312
- . The gene mutated in thiamine-responsive anaemia with diabetes and deafness (TRMA) encodes a functional thiamine transporter. Nat Genet. 1999;22:305–308
-
.
Molecular mechanisms of antifolate transport-deficiency in a methotrexate-resistant MOLT-3 human leukemia cell line.
Blood. 1997;87:2494–2499
- . Variable expression of RFC1 in human leukemia cell lines resistant to antifolates. Cancer Lett. 1998;124:135–142
- . Pyridoxal-5′-phosphate concentration as marker for vitamin-B6-dependent seizures in the newborn. [letter] Lancet. 1984;2(8407):870–871
PII: S0887-8994(01)00407-6
© 2002 Elsevier Science Inc. All rights reserved.
Next »
Pediatric Neurology
Volume 26, Issue 3
, Pages 181-185
, March 2002
