Pediatric Neurology
Volume 27, Issue 5 , Pages 401-403, November 2002

Macrocephaly and epidural involvement of T-cell acute lymphoblastic leukemia

  • Tang-Her Jaing, MD

      Affiliations

    • Hematology/Oncology; Department of Pediatrics; Chang Gung Children’s Hospital; Taoyuan, Taiwan
    • ,
  • Po-Cheng Hung, MD

      Affiliations

    • Neurology; Department of Pediatrics, Chang Gung Children’s Hospital, Taoyuan, Taiwan
    • ,
  • Iou-Jih Hung, MD

      Affiliations

    • Hematology/Oncology; Department of Pediatrics; Chang Gung Children’s Hospital; Taoyuan, Taiwan
    • ,
  • Huei-Shyong Wang, MD

      Affiliations

    • Neurology; Department of Pediatrics, Chang Gung Children’s Hospital, Taoyuan, Taiwan
    • Corresponding Author InformationCommunications should be addressed to: Dr. Wang; Division of Neurology; Department of Pediatrics; Chang Gung Children’s Hospital; 5 Fu-Shin Street; Kwei-Shan 333; Taoyuan, Taiwan.
    • ,
  • Chao-Jan Wang, MD

      Affiliations

    • Department of Diagnostic Radiology; Chang Gung Children’s Hospital; Taoyuan, Taiwan

Received 12 February 2002; accepted 13 May 2002.

Abstract 

We describe a 2-year-old female who presented with macrocephaly and anemia. Magnetic resonance imaging revealed a diffusely enhancing epidural lesion over the sagittal frontoparietal region. Bone marrow examination confirmed the diagnosis of T-cell acute lymphoblastic leukemia. Induction chemotherapy led to hematologic remission and neuroimaging resolution of the mass. This report suggested macrocephaly could be a rare and early manifestation of leukemia in children.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S0887-8994(02)00445-9

Pediatric Neurology
Volume 27, Issue 5 , Pages 401-403, November 2002

Article Tools

* Image Usage & Resolution