Pediatric Neurology
Volume 27, Issue 5 , Pages 388-391 , November 2002

Successful treatment of Ohtahara syndrome with chloral hydrate

  • Pavel Kršek, MD, PhD

      Affiliations

    • Department of Pediatric Neurology; Charles University; Second Medical School; Prague, Czech Republic
    • Corresponding Author InformationCommunications should be addressed to: Dr. Krʂhsek; Department of Pediatric Neurology; Charles University; Second Medical School; Motol University Hospital; Váuvalu 84; CZ 15006 Prague 5, Czech Republic.
    • ,
  • Věra Sebroňová, MD

      Affiliations

    • Department of Pediatric Neurology; Charles University; Second Medical School; Prague, Czech Republic
    • ,
  • Tomáš Procházka, MD

      Affiliations

    • Department of Pediatric Neurology; Charles University; Second Medical School; Prague, Czech Republic
    • ,
  • Alice Maulisová, MA

      Affiliations

    • Department of Pediatric Neurology; Charles University; Second Medical School; Prague, Czech Republic
    • ,
  • Vladimı́r Komárek, MD, PhD

      Affiliations

    • Department of Pediatric Neurology; Charles University; Second Medical School; Prague, Czech Republic

Received 9 April 2002 ,Accepted 12 June 2002.

References 

  1. Ohtahara S, Ishida T, Oka E. On the specific age-dependent epileptic syndrome (The early-infantile epileptic encephalopathy with suppression-burst). No To Hattatsu. 1976;8:270–280
  2. Ohtahara S, Ohtsuka Y, Yamatogi Y, Oka E, Inoue H. Early-infantile epileptic encephalopathy with suppression-bursts. In:  Roger J,  Bureau M,  Dravet CH,  Dreifuss FE,  Perret A,  Wolf P editor. Epileptic syndromes in infancy, childhood, and adolescence. London: John Libbey & Company Ltd; 1992;p. 25–34
  3. Miller SP, Dilenge ME, Meagher-Villemure K, O’Gorman AM, Shevell MI. Infantile epileptic encephalopathy (Ohtahara syndrome) and migrational disorder. Pediatr Neurol. 1998;19:50–54
  4. Clarke M, Gill J, Noronha M, McKinlay I. Early infantile epileptic encephalopathy with suppression burst (Ohtahara syndrome). Dev Med Child Neurol. 1987;29:520–528
  5. Ohno M, Shimotsuji Y, Abe J, Shimada M, Tamiya H. Zonisamide treatment of early infantile epileptic encephalopathy. Pediatr Neurol. 2000;23:341–344
  6. Pedespan JM, Loiseau H, Vital A, Marchal C, Fontan D, Rougier A. Surgical treatment of an early epileptic encephalopathy with suppression-bursts and focal cortical dysplasia. Epilepsia. 1995;36:37–40
  7. Komaki H, Sugai K, Sasaki M, et al.  Surgical treatment of a case of early infantile epileptic encephalopathy with suppression-bursts associated with focal cortical dysplasia. Epilepsia. 1999;40:365–369
  8. Yamatogi Y, Ohtahara S. Early-infantile epileptic encephalopathy with suppression-bursts, Ohtahara syndrome (Its overview referring to our 16 cases). Brain Dev. 2002;24:13–23
  9. Pershad J, Palmisano P, Nichols M. Chloral hydrate (The good and the bad). Pediatr Emerg Care. 1999;15:432–435
  10. Degen R. Seizure therapy in childhood with chloral hydrate–Rectiolen. Med Welt. 1969;64:2098–2100
  11. Shimazaki S, Kuremoto K, Oyama S. Efficacy of rectal diazepam suppository in the prophylaxis of febrile seizures (Comparison with rectal chloral hydrate suppository). No To Hattatsu. 1997;29:278–284
  12. Powell TG, Rosenbloom L. The use of chloral hydrate for refractory childhood epilepsy. Dev Med Child Neurol. 1983;25:524–526
  13. Sahal Khalid M, Schulz H. The treatment and management of emergency status epilepticus. Epilepsia. 1976;17:71–83
  14. Pranzatelli MR, Tate ED. Chloral hydrate for progressive myoclonus epilepsy (A new look at an old drug). Pediatr Neurol. 2001;25:385–389
  15. Daly DD. Epilepsy and syncope. In:  Daly DD,  Pedley TA editor. Current practice of clinical electroencephalography. New York: Raven Press; 1990;p. 269–335

PII: S0887-8994(02)00464-2

Pediatric Neurology
Volume 27, Issue 5 , Pages 388-391 , November 2002

Article Tools

* Image Usage & Resolution