A pediatric patient with sporadic dentatorubral pallidoluysian atrophy
Received 28 May 2002; accepted 24 July 2002.
Abstract
We report a 10-year-old girl with the juvenile type of dentatorubral pallidoluysian atrophy. There were no affected family members, suggesting a sporadic case. Deoxyribonucleic acid analysis for the dentatorubral pallidoluysian atrophy gene was performed, and the CAG trinucleotide repeat numbers in this patient were 61/15. Gene analysis of the patient’s parents was not performed. The molecular mechanisms of the occurrence of sporadic cases have not been clarified.
*Department of Pediatrics, Shiga University of Medical Science, Seta-Tsukinowa, Otsu 520-2192, Japan
Communications should be addressed to: Dr. Takano; Department of Pediatrics; Shiga University of Medical Science; Seta-Tsukinowa; Otsu 520-2192, Japan.
ABSTRACT