Pediatric Neurology
Volume 28, Issue 3 , Pages 231-234 , March 2003

Spontaneous recovery from a medulloblastomaby a female with Gorlin-Goltz syndrome

  • Chih-Wan Su, MD

      Affiliations

    • Division of Pediatric Neurology, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan
    • ,
  • Kuang-Lin Lin, MD

      Affiliations

    • Division of Pediatric Neurology, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan
    • Corresponding Author InformationCommunications should be addressed to:Dr. Lin; Division of Pediatric Neurology, Department of Pediatrics; Chang Gung Children’s Hospital; Chang Gung University; No. 5 Fu-Shin St.; Kweishan, Taoyuan 333, Taiwan.
    • ,
  • Jia-Woei Hou, PhD

      Affiliations

    • Division of Medical Genetics, Department of Pediatrics, Chang Gung Children’s Hospital at Linkou, Taoyuan, Taiwan
    • ,
  • Shih-Ming Jung, MD

      Affiliations

    • Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan
    • ,
  • Erh-Chung Zen, DDS

      Affiliations

    • Division of Oral Surgery, Department of Dentistry, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan

Received 7 May 2002 ,Accepted 3 October 2002.

References 

  1. Evans DG, Farndon PA, Burnell LD, Gattamaneni HR, Birch JM. The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma. Br J Cancer. 1991;64:959–961
  2. Evans DG, Ladusans EJ, Rimmer S, Burnell LD, Thakker N, Farndon PA. Complications of the naevoid basal cell carcinoma syndrome (Results of a population based study). J Med Genet. 1993;30:460
  3. Gorlin RJ. Nevoid basal cell carcinoma syndrome. Medicine (Baltimore). 1987;66:98–113
  4. Shanley SS, Ratcliffe J, Hockey A, et al.  Nevoid basal cell carcinoma syndrome (Reviews of 118 affected individuals). Am J Med Genet. 1994;50:282–290
  5. Cowan R, Hoban P, Kelsey A, Birch JM, Gattamaneni R, Evans DG. The gene for the naevoid basal cell carcinoma syndrome acts as a tumour-suppressor gene in medulloblastoma. Br J Cancer. 1997;76:141–145
  6. O’Malley S, Weitman D, Olding M, Sekhar L. Multiple neoplasms following craniospinal irradiation for medulloblastoma in a patient with nevoid basal cell carcinoma syndrome. J Neurosurg. 1997;86:286–288
  7. Walter AW, Pivnick EK, Bale AE, Kun LE. Complications of the nevoid basal cell carcinoma syndrome (A case report). J Pediatr Hematol Oncol. 1997;19:258–262
  8. Blanchard SB. Odontogenic keratocysts (Review of the literature and report of a case). J Periodontol. 1997;68:306–311
  9. Donatsky O, Hj¢rting-Hansen E. Recurrence of the odontogenic keratocyst in 13 patients with the nevoid basal cell carcinoma syndrome- a 6-year follow-up. Int J Oral Surg. 1980;9:173–179
  10. Ross JS. Intracranial calcification. In:  Haaga JR,  Alfidi RJ editor. Computed tomography of the whole body. 2nd ed. St. Louis: Mosby; 1994;p. 335–7340
  11. Fuchs H, Friedman HS, Halperin EC. Medulloblastoma. In: Black PM, Loeffler JS, editors. Cancer of the nervous system. Cambridge, MA: Blackwell Science, 1997:569–70
  12. Wolter M, Reifenberger J, Sommer C, Ruzicka T, Reifenberger G. Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res. 1997;57:2581–2585
  13. Vortmeyer AO, Stavrou T, Selby D, et al.  Deletion analysis of the adenomatous polyposis coli and PTCH gene loci in patients with sporadic and nevoid basal cell carcinoma syndrome-associated medulloblastoma. Cancer. 1999;85:2662–2667
  14. Al-Anazy FH, Zakzouk SM. Otolaryngological manifestation of Gorlin-Goltz syndrome. J Laryngol Otol. 1997;111:286–289

PII: S0887-8994(02)00618-5

doi: 10.1016/S0887-8994(02)00618-5

Pediatric Neurology
Volume 28, Issue 3 , Pages 231-234 , March 2003

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