Pediatric Neurology
Volume 28, Issue 4 , Pages 271-276 , April 2003

Diagnostic capability of CSF ferritin in children with meningitis

  • Young Ok Kim, MD

      Affiliations

    • Corresponding Author InformationCommunications should be addressed to: Dr. Kim; Department of Pediatrics; Chonnam National University Hospital; 8 Hackdong; Gwangju 501-757 South Korea.
    • Department of Pediatrics, Chonnam National University Hospital, Gwangju, South Korea
    • ,
  • Ji Sun Kang, MD

      Affiliations

    • Department of Pediatrics, Chonnam National University Hospital, Gwangju, South Korea
    • ,
  • Mee Hye Youm, MD

      Affiliations

    • Department of Pediatrics, Chonnam National University Hospital, Gwangju, South Korea
    • ,
  • Young Jong Woo, MD, PhD

      Affiliations

    • Department of Pediatrics, Chonnam National University Hospital, Gwangju, South Korea

Received 9 July 2002 ,Accepted 11 November 2002.

References 

  1. Yogev R. Meningitis. In:  Jenson HB,  Baltimore RS editor. Pediatric infectious disease (principles and practice). 2nd ed. Philadephia: WB Saunders; 2002;p. 630–650
  2. Cherry JD. Aseptic meningitis and viral meningitis. In:  Feigin RD,  Cherry JD editor. Textbook of pediatric infectious disease. 4th ed. Philadephia: WB Saunders; 1998;p. 450–457
  3. Feigin RD, Pearlman E. Bacterial meningitis beyond the neonatal period. In:  Feigin RD,  Cherry JD editor. Textbook of pediatric infectious disease. 4th ed. Philadephia: WB Saunders; 1998;p. 400–429
  4. Cho SH, Lee HB, Lee KS. Clinical study of cerebrospinal fluid lactate levels in children with meningitis. J Korean Pediatr Soc. 2000;43:1068–1073
  5. Corrall CJ, Pepple JM, Moxon ER, Hughes WT. C-reactive protein in spinal fluid of children with meningitis. J Pediatr. 1981;99:365–369
  6. Takahashi S, Oki J, Miyamoto A, Moriyama T, Asano A, Inyaku F, et al. Beta-2-microglobulin and ferritin in cerebrospinal fluid for evaluation of patients with meningitis of different etiologies. Brain Dev. 1999;21:192–199
  7. Ohga S, Aoki T, Okada K, Akeda H, Fujioka K, Ohshima A, et al. Cerebrospinal fluid concentrations of interleukin-1 beta, tumor necrosis factor-alpha, and interferon gamma in bacterial meningitis. Arch Dis Child. 1994;70:123–125
  8. Bullen JJ, Rogers HJ, Griffiths E. Role of iron in bacterial infection. Curr Top Microbiol Immunol. 1978;80:1–35
  9. Bullen JJ. The significance of iron in infection. Rev Infect Dis. 1981;3:1127–1138
  10. Katnik R. A persistent biochemical marker for partially treated meningitis/ventriculitis. J Child Neurol. 1995;10:93–99
  11. Weinberg ED. Iron and infection. Microbiol Rev. 1978;42:45–66
  12. Brock JH. Iron and the outcome of infection. Br Med J. 1986;293:518–520
  13. Weinberg ED. Iron withholding (a defense against infection and neoplasia). Physiol Rev. 1984;64:65–102
  14. Elin RJ, Wolff SM. The role of iron in nonspecific resistance to infection induced by endotoxin. J Immunol. 1974;112:737–745
  15. Milman N, Gradual NA, Olsen TS, Wandall JH, Pederson NS. Cerebrospinal fluid ferritin in patients with meningitis and cerebral infarction or bleeding. Dan Med Bull. 1993;40:490–492
  16. Gruener N, Gozlan O, Goldstein T, Davis J, Besner I, Iancu TC. Iron, transferrin and ferritin in cerebrospinal fluid of children. Clin Chem. 1991;37:263–265
  17. Youm MH, Kim EY, Woo YJ. Change of cerebrospinal fluid ferritin in children with meningitis. J Korean Pediatr Soc. 2000;43:1068–1073
  18. Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiol. 1982;143:29–36
  19. Ashihara Y, Kasahara Y, Nakamura RM. Immunoassays and immunochenistry. In:  Davey FR,  Herman CJ,  McPherson RA,  Pincus MR,  Threatte GA,  Woods GL editor. Clinical diagnosis and management by laboratory methods. 20th ed. Philadephia: WB Saunders; 2001;p. 821–849
  20. Rogers J, Lacroix L, Durmowitz G, Kasschau K, Andriotakis J, Bridges KR. The role of cytokines in the regulation of ferritin expression. Adv Exp Med Biol. 1994;356:127–132
  21. Zandmann-Goddard G, Matzner Y, Konijn AM, Hershko C. Cerebrospinal fluid ferritin in malignant CNS involvement. Cancer. 1986;58:1346–1349
  22. Worwood M, Hourahne D, Jones BM. Accumulation and release of isoferritins during incubation in vitro of human peripheral blood mononuclear cells. Br J Haematol. 1984;56:31–43
  23. Campbell DR, Skikne BS, Cook JD. Cerebrospinal fluid ferritin levels in screening for meningism. Arch Neurol. 1986;43:1257–1260
  24. Taylor EM, Morgan EH. Developmental changes in transferrin and iron uptake by the brain in the rat. Brain Res Dev Brain Res. 1990;55:35–42
  25. Roskams AJ, Connor JR. Iron, transferrin, and ferritin in the rat brain during development and aging. J Neurochem. 1994;63:709–716

PII: S0887-8994(02)00625-2

doi: 10.1016/S0887-8994(02)00625-2

Pediatric Neurology
Volume 28, Issue 4 , Pages 271-276 , April 2003

Article Tools

* Image Usage & Resolution