Pediatric Neurology
Volume 28, Issue 4 , Pages 292-294 , April 2003

Elevated levels of measles antibodies in children with autism

  • Vijendra K. Singh, PhD

      Affiliations

    • Corresponding Author InformationCommunications should be addressed to: Dr. Singh; Biotechnology Center; Utah State University; 4700 Old Main Hill; Logan, Utah, 84322, USA.
    • Department of Biology and Biotechnology Center, Utah State University, Logan, Utah, USA
    • ,
  • Ryan L. Jensen, BS

Received 23 July 2002 ,Accepted 28 October 2002.

References 

  1. Singh VK, Warren RP, Odell JD, Cole P, Warren L. Antibodies to myelin basic protein in children with autistic disorder. Brain Behav Immun. 1993;7:97–103
  2. Singh VK. Plasma increase of interleukin-12 and interferon-gamma (Pathological significance in autism). J Neuroimmunol. 1996;66:143–145
  3. Singh VK, Warren RP, Averett R, Ghaziuddin M. Circulating autoantibodies to neuronal and glial filament proteins in autism. Pediatr Neurol. 1997;16:88–90
  4. Singh VK. Neuro-immunopathogenesis in autism. In:  Berczi I,  Gorczynski R editor. Neuroimmune biology: New foundation of biology. New York: Elsevier; 2001;p. 447–458
  5. Singh VK, Lin SY, Yang VC. Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism. Clin Immunol Immunopathol. 1998;89:105–108
  6. Singh VK, Lin SX, Newell E, Nelson C. Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism. J Biomed Sci. 2002;9:359–364
  7. Weizman A, Weizman R, Szekely GA, Wijsenbeek H, Livni E. Abnormal immune response to brain tissue antigen in the syndrome of autism. Am J Psychiatry. 1982;139:1462–1465
  8. Menage P, Thibault G, Barthelemy C, Lelord G, Bardos P. CD4+ CD45RA+ T lymphocyte deficiency in autistic children (Effect of a pyridoxine-magnesium treatment). Brain Dysfunct. 1992;5:326–333
  9. Chess S, Fernandez P, Korn S. Behavioral consequences of congenital rubella. J Pediatr. 1978;93:699–703
  10. Ivarsson SA, Bjerre I, Vegfors P, Ashfors K. Autism as one of several disabilities in two children with congenital cytomegalovirus infection. Neuropediatrics. 1990;21:102–103
  11. Kawashima H, Mori T, Kashiwagi Y. Detection and sequencing of measles virus from peripheral blood mononuclear cells from patients with inflammatory bowel disease and autism. Digest Dis Sci. 2000;45:723–729
  12. Madhur G. Indian scientists warn of ‘mutant measles’ virus. BMJ. 2001;322:693

PII: S0887-8994(02)00627-6

doi: 10.1016/S0887-8994(02)00627-6

Pediatric Neurology
Volume 28, Issue 4 , Pages 292-294 , April 2003

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