Pediatric Neurology
Volume 28, Issue 5 , Pages 342-346 , May 2003

Encephalopathy as a predictor of magnetic resonance imaging abnormalities in asphyxiated newborns

  • Seth A Kaufman, MD

      Affiliations

    • School of Medicine, University of California at San Francisco, San Francisco, California, USA
  • ,
  • Steven P Miller, MD

      Affiliations

    • Department of Neurology, University of California at San Francisco, San Francisco, California, USA
  • ,
  • Donna M Ferriero, MD

      Affiliations

    • Department of Neurology, University of California at San Francisco, San Francisco, California, USA
    • Department of Pediatrics, University of California at San Francisco, San Francisco, California, USA
  • ,
  • David H Glidden, PhD

      Affiliations

    • Department of Pediatrics, University of California at San Francisco, San Francisco, California, USA
  • ,
  • A.James Barkovich, MD

      Affiliations

    • Department of Neurology, University of California at San Francisco, San Francisco, California, USA
    • Department of Pediatrics, University of California at San Francisco, San Francisco, California, USA
    • Department of Radiology, University of California at San Francisco, San Francisco, California, USA
  • ,
  • J.Colin Partridge, MD, MPH

      Affiliations

    • Department of Pediatrics, University of California at San Francisco, San Francisco, California, USA
    • Corresponding Author InformationCommunications should be addressed to: Dr. Partridge; Neonatal Brain Disorders Center; University of California, San Francisco; 521 Parnassus Ave, Box 0114; San Francisco, CA 94143-0114, USA.

Received 11 June 2002 ,Accepted 17 December 2002.

References 

  1. Volpe JJ. Neurology of the newborn. 4th ed. Philadelphia: WB Saunders; 2001;
  2. Vannucci RC, Perlman JM. Interventions for perinatal hypoxic-ischemic encephalopathy. Pediatrics. 1997;100:1004–1011
  3. Badawi N, Kurinczuk JJ, Keogh JM, et al.  Intrapartum risk factors for newborn encephalopathy (The Western Australian Case-Control Study). BMJ. 1998;317:1554–1558
  4. Badawi N, Kurinczuk JJ, Keogh JM, et al.  Antepartum risk factors for newborn encephalopathy (The Western Australian Case-Control Study). BMJ. 1998;317:1549–1553
  5. Mercuri E, Guzzetta A, Haataja L, et al.  Neonatal neurological examination in infants with hypoxic ischaemic encephalopathy (Correlation with MRI findings). Neuropediatrics. 1999;30:83–89
  6. Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress (A clinical and electroencephalographic study). Arch Neurol. 1976;33:696–705
  7. Wayenberg JL, Vermeylen D, Bormans J, Magrez P, Muller MF, Pardou A. Diagnosis of severe birth asphyxia and early prediction of neonatal neurological outcome in term asphyxiated newborns. J Perinat Med. 1994;22:129–136
  8. Robertson CM, Finer NN. Long-term follow-up of term neonates with perinatal asphyxia. Clin Perinatol. 1993;20:483–500
  9. Thompson CM, Puterman AS, Linley LL, et al.  The value of a scoring system for hypoxic ischaemic encephalopathy in predicting neurodevelopmental outcome. Acta Paediatr. 1997;86:757–761
  10. van de Riet FE, Vandenbussche FPHA, Cessie SL, Keirse MJNC. Newborn assessment and long-term adverse outcome (A systematic review). Am J Obstet Gynecol. 1999;180:1024–1029
  11. Rutherford MA, Pennock JM, Counsell SJ, et al.  Abnormal magnetic resonance signal in the internal capsule predicts poor neurodevelopmental outcome in infants with hypoxic-ischemic encephalopathy. Pediatrics. 1998;102:323–328
  12. Barkovich AJ, Hajnal BL, Vigneron D, et al.  Prediction of neuromotor outcome in perinatal asphyxia (Evaluation of MR scoring systems). AJNR. 1998;19:143–149
  13. Haataja L, Mercuri E, Guzzetta A, et al.  Neurologic examination in infants with hypoxic ischemic encephalopathy at age 9 and 14 months (Use of optimality scores and correlation with magnetic resonance imaging findings). J Pediatr. 2001;138:332–337
  14. Mercuri E, Ricci D, Cowan FM, et al.  Head growth in infants with hypoxic-ischemic encephalopathy (Correlation with neonatal magnetic resonance imaging). Pediatrics. 2000;106:235–243
  15. Finer NN, Robertson CM, Richards RT, Pinnell LE, Peters KL. Hypoxic-ischemic encephalopathy in term neonates (Perinatal factors and outcome). J Pediatr. 1981;98:112–117
  16. Sie LTL, van der Knaap MS, Oosting J, de Vries LS, Lafeber HN, Valk J. MR patterns of hypoxic-ischemic brain damage after prenatal, perinatal or postnatal asphyxia. Neuropediatrics. 2000;31:128–136
  17. Berger R, Garnier Y. Perinatal brain injury. J Perinat Med. 2001;29:85–86
  18. Vexler ZS, Ferriero DM. Molecular and biochemical mechanisms of perinatal brain injury. Semin Neonatol. 2001;6:99–108
  19. Black SM, Bedolli MA, Martinez S, Bristow JD, Ferriero DM, Soifer SJ. Expression of neuronal nitric oxide synthase corresponds to regions of selective vulnerability to hypoxia-ischaemia in the developing rat brain. Neurobiol Dis. 1995;2:145–155
  20. Mellits ED, Holden KR, Freeman JM. Neonatal seizures. II. A multivariate analysis of factors associated with outcome. Pediatrics. 1982;70:177–185
  21. Minchom P, Niswander K, Chalmers I, et al.  Antecedents and outcome of very early neonatal seizures in infants born at or after term. Br J Obstet Gynaecol. 1987;94:431–439
  22. Ekert P, Perlman M, Steinlin M, Hao Y. Predicting the outcome of postasphyxial hypoxic-ischemic encephalopathy within 4 hours of birth. J Pediatr. 1997;131:613–617
  23. McBride MC, Laroia N, Guillet R. Electrographic seizures in neonates correlate with poor neurodevelopmental outcome. Neurology. 2000;55:506–513
  24. Scher MS, Aso K, Beggarly ME, Hamid MY, Steppe DA, Painter MJ. Electrographic seizures in preterm and full-term neonates (Clinical correlates, associated brain lesions, and risk for neurologic sequelae). Pediatrics. 1993;91:128–134
  25. Miller SP, Weiss J, Barnwell A, et al.  Seizure-associated brain injury in term newborns with perinatal asphyxia. Neurology. 2002;58:542–548
  26. Arpino C, Domizio S, Carrieri MP, Brescianini DS, Sabatino MG, Curatolo P. Prenatal and perinatal determinants of neonatal seizures occurring in the first week of life. J Child Neurol. 2001;16:651–656
  27. Sheth RD, Hobbs GR, Mullett M. Neonatal seizures (Incidence, onset and etiology by gestational age). J Perinatol. 1999;19:40–43
  28. Calciolari G, Perlman JM, Volpe JJ. Seizures in the neonatal intensive care unit of the 1980’s (Types, etiologies and timing). Clin Pediatr (Phila). 1988;27:119–123

PII: S0887-8994(03)00015-8

doi: 10.1016/S0887-8994(03)00015-8

Pediatric Neurology
Volume 28, Issue 5 , Pages 342-346 , May 2003