Pediatric Neurology
Volume 28, Issue 5 , Pages 370-378 , May 2003

Post-transplant seizures in infants with hypoplastic left heart syndrome

  • Roshan Raja, DO

      Affiliations

    • Division of Child Neurology, Loma Linda University School of Medicine, Loma Linda, California, USA
  • ,
  • Joyce K Johnston, RN

      Affiliations

    • Department of Surgery (Division of Cardiac Transplantation), Loma Linda University School of Medicine, Loma Linda, California, USA
  • ,
  • James A Fitts, MBA

      Affiliations

    • Department of Surgery (Division of Cardiac Transplantation), Loma Linda University School of Medicine, Loma Linda, California, USA
  • ,
  • Leonard L Bailey, MD

      Affiliations

    • Department of Surgery (Division of Cardiac Transplantation), Loma Linda University School of Medicine, Loma Linda, California, USA
  • ,
  • Richard E Chinnock, MD

      Affiliations

    • Department of Pediatrics, Loma Linda University School of Medicine, Loma Linda, California, USA
  • ,
  • Stephen Ashwal, MD

      Affiliations

    • Division of Child Neurology, Loma Linda University School of Medicine, Loma Linda, California, USA
    • Corresponding Author InformationCommunications should be addressed to: Dr. Ashwal; Division of Pediatric Neurology; Loma Linda University School of Medicine; 11175 Campus St, Ste. A1120G; Loma Linda, CA 92350, USA

Received 5 September 2002 ,Accepted 10 December 2002.

References 

  1. Norwood WI. Hypoplastic left heart syndrome. Ann Thorac Surg. 1991;52:688–695
  2. Chang RK, Chen AY, Klitzner TS. Clinical management of infants with hypoplastic left heart syndrome in the United States, 1988-1997. Pediatrics. 2002;110:292–298
  3. Gutgesell HP, Gibson J. Management of hypoplastic left heart syndrome in the 1990s. Am J Cardiol. 2002;89:842–846
  4. Menache CC, du Plessi AJ, Wessel DL, Jonas RA, Newburger JW. Current incidence of acute neurologic complications after open-heart operations in children. Ann Thorac Surg. 2002;73:1752–1758
  5. Newburger J, Jonas R, Wernovsky G, et al.  A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery. N Engl J Med. 1993;329:1057–1064
  6. Fricker FJ, Griffith BP, Hardesty RL, et al.  Experience with heart transplantation in children. Pediatrics. 1987;79:138–146
  7. Martin AB, Bricker JT, Fishman M, et al.  Neurologic complications of heart transplantation in children. J Heart Lung Transplant. 1992;11:933–942
  8. Dunn JM, Cavarocchi NC, Balsara RK, et al.  Pediatric heart transplantation at St Christopher’s Hospital for Children. J Heart Transplant. 1987;6:334–342
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  10. Du Plessi AJ. Neurologic disorders associated with cardiac disease. In:  Swaiman K,  Ashwal S editor. 3rd ed. Pediatric neurology principles and practice. Vol. 2:St. Louis: MO: Mosby; 1999;p. 1385–1389
  11. Bellinger DC, Jonas RA, Rappaport LA, et al.  Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. N Engl J Med. 1995;332:549–555
  12. Holmes G, Rowe J, Hafford J, Schmidt R, Testa M, Zimmerman A. Prognostic value of the electroencephalogram in neonatal asphyxia. Electroencephalogr Clin Neurophysiol. 1982;53:60–72
  13. Clancy RR, Gaynor JW, Spray T, Wernovsky G, Goin JE. Factors associated with seizures after newborn heart surgery using deep hypothermic circulatory arrest. Poster Presentation. Abstract 1.146. American Epilepsy Society and American Clinical Neurophysiology Society-2001 Joint Meeting. Nov. 30-Dec. 5, 2001, Philadelphia, PA
  14. Lynch BJ, Glauser TA, Canter C, Spray T. Neurologic complications of pediatric heart transplantation. Arch Pediatr Adolesc Med. 1994;148:973–979
  15. McLean RF, Wong BI. Normothermic versus hypothermic cardiopulmonary bypass (Central nervous system outcomes). J Cardiothorac Vasc Anesth. 1996;10:45–52
  16. Shake JG, Peck EA, Marban E, et al.  Pharmacologically induced preconditioning with diazoxide (A novel approach to brain protection). Ann Thorac Surg. 2001;72:1849–1854
  17. McConnell JR, Fleming WH, Chu WK, et al.  Magnetic resonance imaging of the brain in infants and children before and after cardiac surgery. Am J Dis Child. 1990;144:374–378
  18. Baum M, Chinnock R, Ashwal S, Peverini R, Trimm F, Bailey L. Growth and neurodevelopmental outcome of infants undergoing heart transplantation. J Heart Lung Transplant. 1993;12:S211–217

PII: S0887-8994(03)00018-3

doi: 10.1016/S0887-8994(03)00018-3

Pediatric Neurology
Volume 28, Issue 5 , Pages 370-378 , May 2003