Pediatric Neurology
Volume 29, Issue 2 , Pages 148-150 , August 2003

Insights into the pathogenesis of cerebral lesions in incontinentia pigmenti

  • Sabine J Hennel, MD

      Affiliations

    • Department of Pediatrics, Murdoch Children’s Research Institute and Howard Florey Institute, and Royal Women’s and Royal Children’s Hospital, Melbourne, Australia
    • ,
  • Paul G Ekert, MD, PhD

      Affiliations

    • Department of Pediatrics, Murdoch Children’s Research Institute and Howard Florey Institute, and Royal Women’s and Royal Children’s Hospital, Melbourne, Australia
    • ,
  • Joseph J Volpe, MD

      Affiliations

    • Department of Neurology, Children’s Hospital and Harvard Medical School, Boston, Massachuasetts, USA
    • ,
  • Terrie E Inder, MD

      Affiliations

    • Department of Pediatrics, Murdoch Children’s Research Institute and Howard Florey Institute, and Royal Women’s and Royal Children’s Hospital, Melbourne, Australia
    • Department of Neurology, Children’s Hospital and Harvard Medical School, Boston, Massachuasetts, USA
    • Corresponding Author InformationCommunications should be addressed to: Dr. Inder; Murdoch Children’s Research Institute and Howard Florey Institute; Royal Children’s Hospital; Flemington Rd; Parkville VIC 3052, Australia.

Received 24 October 2002 ,Accepted 17 February 2003.

References 

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  2. Carney RG. Incontinentia pigmenti (A world statistical analysis). Arch Dermatol. 1976;112:535–542
  3. Kasmann-Kellner B, Jurin-Bunte B, Ruprecht KW. Incontinentia pigmenti (Bloch-Sulzberger-Syndrome) (Case report and differential diagnostic related dermato-occular syndromes). Ophthalmologica. 1999;213:63–69
  4. Lee AG, Goldberg MF, Gillard JH, et al.  Intracranial assessment of incontinentia pigmenti using magnetic resonance imaging, angiography and spectroscopic imaging. Arch Pediatr Adolesc Med. 1995;149:573–580
  5. Manago S, Barbagallo A. Incontinentia pigmenti (Clinical and neuroradiologic features). Brain Dev. 1993;15:362–366
  6. Chatkupt S, Gozo AO, Wolansky LJ, et al.  Characteristic MR findings in a neonate with incontinentia pigment. AJR. 1993;160:372–374
  7. Shuper A, Bryan RN, Singer HS. Destructive encephalopathy in incontinentia pigmenti (A primary disorder?). Pediatr Neurol. 1990;2:137–140
  8. Aydingoz U, Midia M. Central nervous system involvement in incontinentia pigmenti (Cranial MRI of two siblings). Pediatr Neuroradiology. 1998;40:364–366
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  10. Kasai T, Kato Z, Matsui E, et al.  Cerebral infarction in incontinentia pigmenti (The first report of a case evaluated by single photon emission computed tomography). Acta Paediatr. 1997;86:665–667
  11. Sasaki M, Hanaoka S, Suzuki H, et al.  Cerebral white matter lesions in a case of incontinentia pigmenti with infantile spasms, mental retardation and left hemiparesis. Brain Dev. 1991;23:278–283
  12. Yoshikawa H, Uehara Y, Abe T, et al.  Disappearance of a white matter lesion in incontinentia pigmenti. Pediatr Neurol. 2000;23:364–367
  13. Siemes H, Schneider H, Dening D, et al.  Encephalitis in two members of a family with incontinentia pigmenti (Bloch-Sulzberger Syndrome) (The possible role of inflammation in the pathogenesis of CNS involvement). Eur J Pediatr. 1978;129:103–115
  14. Holmstrom G, Thoren K. Ocular manifestations of incontinentia pigmenti. Acta Ophthalmol Scand. 2000;78:348–353
  15. Goldberg MF. The blinding mechanisms of incontinentia pigmenti. Trans Am Ophthalmol Soc. 1994;92:167–176
  16. Goldberg MF. Macular vasculopathy and its evolution in incontinentia pigmenti. Ophthalmic Paediatr Gene. 1998;19:141–148
  17. Goldberg MF, Custis PH. Retinal and other manifestations of incontinentia pigmenti (Bloch-Sulzberger Syndrome). Ophthalmology. 1993;100:1645–1654
  18. Husson B, Rodesch G, Lasjaunias P, et al.  Magnetic resonance angiography in childhood arterial brain infarcts (A comparative study with contrast angiography). Stroke. 2002;33:1280–1285
  19. Pelligrino RJ, Shah AJ. Vascular occlusion associated with incontinentia pigmenti. Pediatr Neurol. 1994;10:73–74
  20. Volpe JJ. Neurobiology of periventricular leukomalacia in the premature infant. Pediatr Res. 2001;50:553–562

PII: S0887-8994(03)00150-4

doi: 10.1016/S0887-8994(03)00150-4

Pediatric Neurology
Volume 29, Issue 2 , Pages 148-150 , August 2003

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