Pediatric Neurology
Volume 29, Issue 3 , Pages 236-238 , September 2003

Progressive muscle weakness after high-dose steroids in two children with CIDP

  • Kevin M Rostasy, MD

      Affiliations

    • Department of Pediatrics and Neuropediatrics, Georg-August-Universität Göttingen, Göttingen, Germany.
    • Corresponding Author InformationCommunications should be addressed to: Dr. Rostasy; Pediatric Neurology; Georg-August-University of Göttingen; Robert-Koch-Strasse 40; 37075 Göttingen, Germany.
  • ,
  • Katharina Diepold, MD

      Affiliations

    • Department of Pediatrics and Neuropediatrics, Georg-August-Universität Göttingen, Göttingen, Germany.
  • ,
  • Johannes Buckard, MD

      Affiliations

    • Department of Pediatrics and Neuropediatrics, Georg-August-Universität Göttingen, Göttingen, Germany.
  • ,
  • Knut Brockmann, MD

      Affiliations

    • Department of Pediatrics and Neuropediatrics, Georg-August-Universität Göttingen, Göttingen, Germany.
  • ,
  • Bernd Wilken, MD

      Affiliations

    • Department of Pediatrics and Neuropediatrics, Georg-August-Universität Göttingen, Göttingen, Germany.
  • ,
  • Folker Hanefeld, MD

      Affiliations

    • Department of Pediatrics and Neuropediatrics, Georg-August-Universität Göttingen, Göttingen, Germany.

Received 17 December 2002 ,Accepted 17 March 2003.

References 

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  2. Ryan MM, Grattan-Smith PJ, Procopis PG, Morgan G, Ouvrier RA. Childhood chronic inflammatory demyelinating polyneuropathy (Clinical course and long-term outcome). Neuromuscul Disord. 2000;10:398–406
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  10. Larsson L, Li X, Edstrom L, et al.  Acute quadriplegia and loss of muscle myosin in patients treated with nondepolarizing neuromuscular blocking agents and corticosteroids (Mechanisms at the cellular and molecular levels). Crit Care Med. 2000;28:34–45
  11. Mastaglia FL. Adverse effects of drugs on muscle. Drugs. 1982;24:304–321
  12. Rouleau G, Karpati G, Carpenter S, Soza M, Prescott S, Holland P. Glucocorticoid excess induces preferential depletion of myosin in denervated skeletal muscle fibers. Muscle Nerve. 1987;10:428–438
  13. Danon MJ, Carpenter S. Myopathy with thick filament (myosin) loss following prolonged paralysis with vercuronium during steroid treatment. Muscle Nerve. 1991;14:1131–1139
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PII: S0887-8994(03)00222-4

doi: 10.1016/S0887-8994(03)00222-4

Pediatric Neurology
Volume 29, Issue 3 , Pages 236-238 , September 2003