Pediatric Neurology
Volume 29, Issue 3 , Pages 256-259 , September 2003

Brainstem cranial-nerve lesions in an infant with hypoxic cerebral injury

  • Seiichi Sugama, MD

      Affiliations

    • Department of Pediatrics, Tokyo Metropolitan Maternity and Child Health Institute, Tokyo, Japan
    • Corresponding Author InformationCommunications should be addressed to: Dr. Sugama; Department of Pediatrics; Tokyo Metropolitan Ohtsuka Hospital; 2-8-1 Minami-Ohtsuka, Toshima-ku; Tokyo 170-8476, Japan.
    • ,
  • Masamichi Ariga, MD

      Affiliations

    • Department of Pediatrics, Tokyo Metropolitan Maternity and Child Health Institute, Tokyo, Japan
    • ,
  • Eiichi Hoashi, MD

      Affiliations

    • Department of Pediatrics, Tokyo Metropolitan Maternity and Child Health Institute, Tokyo, Japan
    • ,
  • Yoshikatsu Eto, MD, PhD

      Affiliations

    • Department of Pediatrics, The Jikei University School of Medicine, Tokyo, Japan

Received 3 December 2002 ,Accepted 17 March 2003.

References 

  1. Volpe JJ. Hypoxic-ischemic encephalopathy: Neuropathology and pathogenesis. In:  Volpe JJ editors. Neurology of the newborn. 3rd ed.. Philadelphia: WB Saunders; 1995;p. 279–313
  2. Barkovich AJ, Hallam D. Neuroimaging perinatal hypoxic-ischemic injury. MRDD Res Rev. 1997;3:28–41
  3. Leech RW, Alvord EC. Anoxic-ischemic encephalopathy in the human neonatal period (The significance of brainstem involvement). Arch Neurol. 1977;34:109–113
  4. Leech RW, Brumback RA. Massive brainstem necrosis in the human neonate (Presentation of three cases with review of the literature). J Child Neurol. 1988;3:258–262
  5. Pindur J, Capin DM, Johnson MI, et al.  Cystic brain stem necrosis in a premature infant after prolonged bradycardia. Acta Neuropathol. 1992;83:667–669
  6. Norman MG. Antenatal neuronal loss and gliosis of the reticular formation, thalamus, and hypothalamus (A report of three cases). Neurology. 1972;22:910–916
  7. Dambska M, Laure-Kamionowska M, Liebhart M. Brainstem lesions in the course of chronic fetal asphyxia. Clin Neuropathol. 1987;6:110–115
  8. Roland EH, Hill A, Norman MG, et al.  Selective brainstem injury in an asphyxiated newborn. Ann Neurol. 1988;23:89–92
  9. Voit T, Lemburg P. Damage of thalamus and basal ganglia in asphyxiated full-term neonates. Neuropediatrics. 1987;18:176–181
  10. Pasternak JF, Predey TA, Milhael MA. Neonatal asphyxia (Vulnerability of basal ganglia, thalamus, and brainstem). Pediatr Neurol. 1991;7:147–149
  11. Barkovich AJ. MR and CT evaluation of profound neonatal and infantile asphyxia. Am J Neuroradiol. 1992;13:959–972
  12. Myers RE. Two patterns of perinatal brain damage and the condition of occurrence. Am J Obstet Gynecol. 1977;112:246–276
  13. Azzrarelli B, Caldemeyer KS, Phillips JP, et al.  Hypoxic-ischemic encephalopathy in areas of primary myelination (A neuroimaging and PET study). Pediatr Neurol. 1996;14:108–116
  14. McDonald J, Johnston M. Physiological and pathophysiological roles of excitatory amino acids during central nervous system development. Brain Res Rev. 1990;15:41–70
  15. Watson C. In: Atlas of brain and spine: Basic human neuroanatomy: An introductory atlas. 5th ed.. Boston: Little Brown; 1995;p. 98–228

PII: S0887-8994(03)00232-7

doi: 10.1016/S0887-8994(03)00232-7

Pediatric Neurology
Volume 29, Issue 3 , Pages 256-259 , September 2003

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