Pediatric Neurology
Volume 30, Issue 4 , Pages 271-277 , April 2004

Risk factors for developing epilepsy after neonatal seizures

  • Luis Fernando Garcias Da Silva, MD

      Affiliations

    • Division of Neurology and Clinical Neurophysiology Laboratory, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul School of Medicine, Porto Alegre, Brazil
    • ,
  • Magda Lahorgue Nunes, MD, PhD

      Affiliations

    • Division of Neurology and Clinical Neurophysiology Laboratory, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul School of Medicine, Porto Alegre, Brazil
    • Corresponding Author InformationCommunications should be addressed to:Dr. Nunes; Division of Neurology; Hospital São Lucas; Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) School of Medicine; Av. Ipiranga 6690, cj 220; 90610-000 Porto Alegre, RS, Brazil.
    • ,
  • Jaderson Costa Da Costa, MD, PhD

      Affiliations

    • Division of Neurology and Clinical Neurophysiology Laboratory, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul School of Medicine, Porto Alegre, Brazil

Received 21 May 2003 ,Accepted 17 September 2003.

References 

  1. Scher MS, Painter MJ. Controversies concerning neonatal seizures. Pediatr Clin North Am. 1989;36:281–311
  2. Lombroso CT. Prognosis in neonatal seizures. In:  Delgado-Escueta AV,  Wasterlain CG,  Treiman DM,  Porter RJ editor. Status epilepticus: Mechanisms of brain damage and treatment. Advances in Neurology. New York: Raven Press; 1983;p. 101–113
  3. Lombroso CT. Neonatal seizures. Historic notes and present controversies. Epilepsia. 1996;37(Suppl.):S5–13
  4. Erickson M, Zetterstrom R. Neonatal convulsions (Incidence and causes in the Stockholm area). Acta Pediatr Scand. 1979;68:807–811
  5. Bergman I, Painter MJ, Hirsh RP, Crumine PK, David R. Outcome of neonates with convulsions treated in an intensive care unit. Ann Neurol. 1983;14:642–647
  6. Mizrahi EM, Kellaway P. Characterization and classification of neonatal seizures. Neurology. 1987;37:1837–1844
  7. Scher MS. Seizures in the newborn infant (Diagnosis, treatment and outcome). Clin Perinatol. 1997;24:735–772
  8. Lombroso CT, Nunes ML, Da Costa JC. Crises convulsivas no recém-nascido. In:  Da Costa JC,  Palmini AL,  Yacubian EMT,  Cavalheiro EA editor. Fundamentos neurobiológicos das epilepsias: Aspectos clínicos e cirúrgicos. São Paulo: Lemos-Editorial; 1998;p. 163–201
  9. Bernes SM, Kaplan AM. Evolution of neonatal seizures. Pediatr Clin North Am. 1994;41:1069–1104
  10. Arpino C, Domizio S, Carrieri MP, Brescianini S, Sabatino G, Curatolo P. Prenatal and perinatal determinants of neonatal seizures occurring in the first week of life. J Child Neurol. 2001;16:651–655
  11. Keen JH, Lee D. Sequelae of neonatal convulsions (Study of 112 infants). Arch Dis Child. 1973;48:542–546
  12. Denis J. Neonatal convulsions (Etiology, late neonatal status and long-term outcome). Dev Med Child Neurol. 1978;20:143–158
  13. Curatolo P, Arpino C, Stazi MA, Medda E. Risk factors for the co-occurrence of partial epilepsy, cerebral palsy and mental retardation. Dev Child Neurol. 1995;37:776–782
  14. Mellits ED, Holden KR, Freeman JM. Neonatal seizures II (A multivariate analysis of factors associated with outcome). Pediatrics. 1982;70:177–185
  15. Clancy RR, Legido A. Postnatal epilepsy after EEG-confirmed neonatal seizures. Epilepsia. 1991;32:69–76
  16. Volpe JJ. Neurology of the newborn. 4th ed. Philadelphia: WB Saunders; 2001; 331-94
  17. Legido A, Clancy R, Berman P. Neurologic outcome after electroencephalographically proven neonatal seizures. Pediatrics. 1991;88:583–596
  18. Fernandes JG. Epidemiologia das crises epilépticas em Porto Alegre: Um estudo populacional. Tese de Doutorado. Porto Alegre: UFRGS; 1993;
  19. Commission on Classification and Terminology of the International League Against Epilepsy . Proposal for classification of epilepsies and epileptic syndromes. Epilepsia. 1989;30:389–399
  20. Lombroso CT. Neonatal EEG polygraphy in normal and abnormal newborns. In:  Niedermayer E,  Lopes da Silva F editor. Electroencephalography: Basic principles, clinical applications and related fields. Baltimore: Urban e Schwarzemberg; 1993;p. 803–875
  21. Lanska MJ, Lanska D, Baumann RJ, Allen SL, Slone KG, Kryscio RJ. Interobserver variability in the classification of neonatal seizures based on medical record data. Pediatr Neurol. 1996;15:120–123
  22. Hauser WA, Annegers JF. Epidemiology of epilepsy. In:  Laidlaw J,  Richens A,  Chadwick D editor. A textbook of epilepsy. London: Churchill Livingstone; 1993;p. 23–45
  23. Sander JWA, Schorvon SD. . Incidence and prevalence studies in epilepsy and their methodological problems (A review). J Neurol Neurosurg Psychiatr. 1987;50:829–839
  24. Ronen GM, Penney S, Andrews W. The epidemiology of clinical neonatal seizures in Newfoundland (A population based study). J Pediatr. 1999;134:71–75
  25. Lanska MJ, Lanska DJ, Baumann RJ, Kryscio R. A population-based study of neonatal seizures in Fayette county, Kentucky. Neurology 1195;45:224-32
  26. Sander JWA, Schorvon SD. Epidemiology of epilepsies. J Neurol Neurosurg Psychiatr. 1996;61:433–443
  27. Lombroso CT. Early myoclonic encephalopathy, early infantile epileptic encephalopathy, and benign and severe infantile myoclonic epilepsies (A critical review and personal contributions). J Clin Neurophysiol. 1990;7:380–408
  28. Watanabe K. Etiological and preventive aspects of epileptology in the developing nervous system. In:  Akimato H,  Seino M,  Ward AA editor. Advances in epileptology. New York: Raven Press; 1982;p. 77–82
  29. Catlin EA, Carpenter MW, Brann BS, et al.  The Apgar score revised (Influence of gestational age). J Pediatr. 1986;109:865–868
  30. Silva EA, Nunes ML, Da Costa JC. Correlation of EEG and polysomnographic features with follow-up in asphyxiated newborns. Electroencephalogr Clin Neurophysiol. 1993;87:106
  31. Holmes GL, Gairsa JL, Chevassus AV, Louis N, Ben-Ary Y. Consequences of neonatal seizures in the rat (Morphological and behavioral effects). Ann Neurol. 1998;44:845–857
  32. Nelson KB, Ellenberg JH. Neonatal signs as predictors of cerebral palsy. Pediatrics. 1979;64:225–232
  33. Annegers JF, Hauser WA, Beghi E. The risk of unprovoked seizures after encephalitis and meningitis. Neurology. 1998;38:1407–1410
  34. Rose AL, Lombroso CT. A study of clinical pathological and electroencephalographic features in 137 full-term babies with a long-term follow-up. Pediatrics. 1970;45:404–425
  35. Dreyfus-Brissac C, Monod N. The EEG of full-term newborns and premature infants. In:  Lairy GC editors. The evolution of the EEG from birth to adulthood. Amsterdam: Elsevier; 1975;p. 6–23
  36. Nunes ML, Da Costa JC, Taufer L, Da Silveira CM. Value of the EEG characterization and prognosis of neurological diseases in premature infants. Ar Qneuropsiquiatr. 1995;53(3-B):625–630
  37. Oliveira AJ, Nunes ML, Da Costa JC. Polysomnography in neonatal seizures. Clin Neurophyisiol. 2000;111(Suppl. 2):S74–80
  38. Oliveira AJ, Nunes ML, Haertel LM, Reis FM, Da Costa JC. Duration of EEG patterns in neonates: New evidence for clinical and prognostic significance of brief rhythmic discharges. Clin Neurophysiol. 2000;111:1646–1653
  39. Rowe JC, Holmes GL, Hafford J, et al.  Prognostic value of the electroencephalogram in term and preterm infants following neonatal seizures. Electroencephalogr Clin Neurophysiol. 1985;60:183–196

PII: S0887-8994(03)00536-8

doi: 10.1016/j.pediatrneurol.2003.09.015

Pediatric Neurology
Volume 30, Issue 4 , Pages 271-277 , April 2004

Article Tools

* Image Usage & Resolution