Pediatric Neurology
Volume 32, Issue 5 , Pages 300-306 , May 2005

Corticosteroids for the Treatment of Landau-Kleffner Syndrome and Continuous Spike-Wave Discharge During Sleep

  • D. Barry Sinclair, MD

      Affiliations

    • Corresponding Author InformationCommunications should be addressed to: Dr. Sinclair; Director, Division of Pediatric Neurology; 2C3 Walter Mackenzie Health Sciences Center; University of Alberta; Edmonton, AB T6G 2R7; Canada.
  • ,
  • Thomas J. Snyder, PhD

Received 3 August 2004 ,Accepted 28 December 2004.

References 

  1. Landau WM , Kleffner FR . Syndrome of acquired aphasia with convulsive disorder in children . Neurology . 1957;7:523–530
  2. Beaumanoir A . The Landau-Kleffner syndrome . In:  Roger J ,  Dravet C ,  Bureau M ,  Driefuss FE ,  Wolf P editor. Epileptic syndromes in infancy, childhood and adolescence . 2nd ed.. London: J. Libbey; 1992;p. 231–243
  3. Deonna TW . Acquired epileptiform aphasia in children (Landau-Kleffner syndrome) . J Clin Neurophysiol . 1991;9:288–298
  4. Rapin I , Mattis S , Rowan AJ , Golden GG . Verbal auditory agnosia and seizures in children . Dev Med Child Neurol . 1977;19:192–207
  5. Bishop DVM . Age of onset and outcome in “acquired aphasia with convulsive disorder” (Landau-Kleffner syndrome) . Dev Med Child Neurol . 1985;27:705–712
  6. Mantovani JF , Landau WM . Acquired aphasia with convulsive disorder (Course and prognosis) . Neurology . 1980;30:524–529
  7. Paguier PF , Van Dongen HR , Loonen CB . The Landau-Kleffner syndrome or acquired aphasia with convulsive disorder (Long-term follow up of six children and review of the recent literature) . Arch Neurol . 1992;49:354–359
  8. Rossi PG , Parmeggiani A , Posar A , Scaduto MC , Chiodo S , Vatt G . Landau-Kleffner syndrome (LKS) (Long-term follow up and links with electrical status epilepticus during sleep (ESES)) . Brain Devel . 1999;21:90–98
  9. Liu XY , Wong V . Spectrum of epileptic syndromes with electrical status epilepticus during sleep in children . Pediatr Neurol . 2000;22:371–379
  10. Hirsch E , Marescaux C , Maguet P , et al.   Landau-Kleffner syndrome (A clinical and EEG study of five cases) . Epilepsia . 1990;31(6):756–767
  11. Deonna T , Peter C , Zeigler HL . Adult follow up of the acquired aphasia-epilepsy syndrome of childhood (Report of seven cases) . Neuropediatrics . 1989;20:132–138
  12. Feekery CJ , Parry-Fielder B , Hopkins TJ . Landau-Kleffner syndrome (Six patients including discordant monozygotic twins) . Pediatr Neurol . 1993;9:49–53
  13. Guerreiro MM , Camargo EE , Kato M , et al.   Brain single photon emission computed tomography imaging in Landau-Kleffner syndrome . Epilepsia . 1996;37(1):60–67
  14. McKinney W , McGreal DA . An aphasic syndrome in children . Can Med Assoc J . 1994;110:637–639
  15. Marescaux C , Hirsch E , Finck S . Landau-Kleffner syndrome (A pharmacologic study of five cases) . Epilepsia . 1990;31:768–777
  16. Appleton R , Hughes A , Beirae M , Acomb B . Vigabatrin in Landau-Kleffner syndrome . Dev Med Child Neurol . 1993;35:457–458
  17. Lermen P , Lerman-Sagie T , Kivity S . Effects of early corticosteroid therapy for Landau-Kleffner syndrome . Dev Med Child Neurol . 1991;33:257–260
  18. Tsuru T , Mori M , Mizuguchi M , Momoi MY . Effects of high dose intravenous corticosteroid therapy in Landau-Kleffner syndrome . Pediatr Neurol . 2000;22:145–147
  19. Stefanatos GA , Grover W , Geller E . Case study (Corticosteroid treatment of language regression in pervasive developmental disorder) . J Am Acad Child Adolesc Psychiatry . 1995;34(8):1107–1111
  20. Sinclair DB . Prednisone therapy in childhood epilepsy . Pediatr Neurol . 2003;28:194–198
  21. Mikati MA , Saab R . Successful use of intravenous immunoglobulin as initial monotherapy in Landau-Kleffner syndrome . Epilepsia . 2000;41(7):880–886
  22. Lagae LG , Silberstein J , Gillis PL , Casaer PJ . Successful use of intravenous immunoglobulins in Landau-Kleffner syndrome . Pediatr Neurol . 1998;18:165–168
  23. Morrell F , Whisler WM , Smith MC , et al.   Landau-Kleffner syndrome (Treatment with subpial intracortical transection) . Brain . 1995;118:1529–1546
  24. Grote CL , Van Slyke P , Hoeppner JB . Language outcome following multiple subpial transection for Landau-Kleffner syndrome . Brain . 1999;122:561–566
  25. Ness R , Gross A , Wisoff J , Devinsky O . Outcome of multiple subpial transections for autistic epileptiform regression . Pediatr Neurol . 1999;21:464–470

PII: S0887-8994(05)00030-5

doi: 10.1016/j.pediatrneurol.2004.12.006

Pediatric Neurology
Volume 32, Issue 5 , Pages 300-306 , May 2005