Pediatric Neurology
Volume 33, Issue 3 , Pages 162-165 , September 2005

Chorioamnionitis and Neonatal Encephalopathy in Term Infants With Fetal Acidemia: Histopathologic Correlations

  • Lina Shalak, MD

      Affiliations

    • Department of Pediatrics, University of Texas, Southwestern Medical Center, Dallas, Texas
    • ,
  • Sarah Johnson-Welch, MD

      Affiliations

    • Department of Pathology, University of Texas, Southwestern Medical Center, Dallas, Texas
    • ,
  • Jeffrey M. Perlman, MB

      Affiliations

    • Department of Pediatrics; Weill Cornell Medical Center, New York, New York
    • Corresponding Author InformationCommunications should be addressed to: Dr. Perlman; Department of Pediatrics; Weill Cornell Medical Center; 525 East 68th Street N-506; New York, NY 10021.

Received 12 November 2004 ,Accepted 4 April 2005.

References 

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  2. Wu YW . Systematic review of chorioamnionitis and cerebral palsy . Ment Retard Dev Disabil Res Rev . 2002;8:25–29
  3. Wu YW , Escobar GJ , Grether JK , Croen LA , Greene JD , Newman TB . Chorioamnionitis and cerebral palsy in term and near-term infants . JAMA . 2003;290:2677–2684
  4. Willoughby RE , Nelson KB . Chorioamnionitis and brain injury . Clin Perinatol . 2002;29:603–621
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  11. Perlman JM , Risser R . Severe fetal acidemia (Neonatal neurologic features and short-term outcome) . Pediatr Neurol . 1993;9:277–282
  12. Shalak LF , Perlman JM . Infection markers and early signs of neonatal encephalopathy in the term infant . Ment Retard Dev Disabil Res Rev . 2002;8:14–19
  13. Smulian JC , Bhandari V , Vintzileos AM , et al.   Intrapartum fever at term (Serum and histologic markers of inflammation) . Am J Obstet Gynecol . 2003;188:269–274
  14. Yoon BH , Romero R , Park JS , et al.   Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years . Am J Obstet Gynecol . 2000;182:675–681
  15. De Felice C , Toti P , Laurini RN , et al.   Early neonatal brain injury in histological chorioamnionitis . J Pediatr . 2001;138:101–104
  16. Vigneswaran R , Aitchison SJ , McDonald HM , Khong TY , Hiller JE . Cerebral palsy and placental infection (A case-cohort study) . BMC Pregnancy Childbirth . 2004;4:1–21
  17. Baud O , Emilie D , Pelletier E , et al.   Amniotic fluid concentrations of interleukin-1beta, interleukin-6 and TNF-alpha in chorioamnionitis before 32 weeks of gestation (Histological associations and neonatal outcome) . Br J Obstet Gynaecol . 1999;106:72–77
  18. Nelson B , Grether JK , Dambrosia JM , et al.   Neonatal cytokines and cerebral palsy in very preterm infants . Pediatr Res . 2003;53:600–607
  19. Viscardi RM , Muhumuza CK , Rodriquez A , et al.   Inflammatory markers in intrauterine infection and fetal blood and cerebrospinal fluid compartments are associated with adverse pulmonary and neurologic outcomes in preterm infants . Pediatr Res . 2004;55:1009–1017

PII: S0887-8994(05)00226-2

doi: 10.1016/j.pediatrneurol.2005.04.005

Pediatric Neurology
Volume 33, Issue 3 , Pages 162-165 , September 2005

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