Pediatric Neurology
Volume 33, Issue 4 , Pages 285-288, October 2005

The Pharyngeal-Cervical-Brachial Form of Guillain-Barré Syndrome in Childhood

  • Kavitha D. Mogale, MD

      Affiliations

    • T.Y. Nelson Department of Neurology and Neurosurgery, The Children’s Hospital at Westmead, Westmead NSW, Australia
    • Corresponding Author InformationCommunications should be addressed to: Ms Ryan; Senior Lecturer, Discipline of Paediatrics and Child Health; University of Sydney; The Children’s Hospital at Westmead; Locked Bag 4001; Westmead NSW 2145, Australia.
    • ,
  • Jayne H. Antony, MD, PhD

      Affiliations

    • T.Y. Nelson Department of Neurology and Neurosurgery, The Children’s Hospital at Westmead, Westmead NSW, Australia
    • ,
  • Monique M. Ryan, M Med

      Affiliations

    • T.Y. Nelson Department of Neurology and Neurosurgery, The Children’s Hospital at Westmead, Westmead NSW, Australia
    • Discipline of Paediatrics and Child Health, University of Sydney, Sydney NSW, Australia.

Received 7 January 2005; accepted 18 April 2005.

Variant forms of the Guillain-Barré syndrome are characterized by their localized or regional involvement of the peripheral and autonomic nerves. As there is no single clinical or serologic marker for Guillain-Barré syndrome, diagnosis of this condition is based upon consistent clinical, laboratory, and neurophysiologic findings, with exclusion of other conditions mimicking this disorder. Recognition of atypical cases enables anticipatory monitoring for disease complications and identifies therapeutic options for affected children. A regional variant with predominant facial, neck, and arm weakness without sensory loss has been reported in adults but only rarely described in childhood. This study reports clinical and neurophysiologic findings in two children with the pharyngeal-cervical-brachial form of Guillain-Barré syndrome. These are the youngest cases of this uncommon disorder reported to date.

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PII: S0887-8994(05)00237-7

doi:10.1016/j.pediatrneurol.2005.04.012

Pediatric Neurology
Volume 33, Issue 4 , Pages 285-288, October 2005

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