Pediatric Neurology
Volume 34, Issue 1 , Pages 51-54 , January 2006

Hypomelanosis of Ito Associated With Precocious Puberty

  • Beth M. Rutland, MD

      Affiliations

    • Departments of Pathology, University of South Alabama, Mobile, Alabama
    • ,
  • Mark A. Edgar, MD

      Affiliations

    • Memorial Sloan-Kettering Cancer Center, New York, New York
    • ,
  • Marcelo G. Horenstein, MD

      Affiliations

    • Departments of Pathology, University of South Alabama, Mobile, Alabama
    • The Dermatology Group, Verona, New Jersey
    • Corresponding Author InformationCommunications should be addressed to: Dr. Horenstein; Director of Dermatopathology, The Dermatology Group; 60 Pompton Ave.; Verona, NJ 07044

Received 22 April 2005 ,Accepted 26 May 2005.

References 

  1. Ito M . Studies on melanin . Tohoku J Exp Med . 1952;55:1–104
  2. Ruggieri M , Pavone L . Hypomelanosis of Ito (Clinical syndrome or just phenotype?) . J Child Neurol . 2000;15:635–644
  3. Ruggieri M , Tigano G , Mazzone D , Tine A , Pavone L . Involvement of the white matter in hypomelanosis of Ito (incontinentia pigmenti achromians) . Neurology . 1996;46:485–492
  4. Nehal KS , PeBenito R , Orlow SJ . Analysis of 54 cases of hypopigmentation and hyperpigmentation along the lines of Blaschko . Arch Dermatol . 1996;132:1167–1170
  5. Sybert VP . Hypomelanosis of Ito . Pediatr Dermatol . 1990;7:74–76
  6. Hatchwell E . Hypomelanosis of Ito and X;autosome translocations (A unifying hypothesis) . J Med Genet . 1996;33:177–183
  7. Pascual-Castroviejo I , Roche C , Martinez-Bermejo A , et al.   Hypomelanosis of ITO. A study of 76 infantile cases . Brain Dev . 1998;20:36–43
  8. Hennel SJ , Ekert PG , Volpe JJ , Inder TE . Insights into the pathogenesis of cerebral lesions in incontinentia pigmenti . Pediatr Neurol . 2003;29:148–150
  9. Ono J , Harada K , Kodaka R , Ishida M , Okada S . Regional cortical dysplasia associated with suspected hypomelanosis of Ito . Pediatr Neurol . 1997;17:252–254
  10. Ross DL , Liwnicz BH , Chun RW , Gilbert E . Hypomelanosis of Ito (incontinentia pigmenti achromians)—a clinicopathologic study (Macrocephaly and gray matter heterotopias) . Neurology . 1982;32:1013–1016
  11. Fujino O , Hashimoto K , Fujita T , et al.   Clinico-neuropathological study of incontinentia pigmenti achromians—an autopsy case . Brain Dev . 1995;17:425–427
  12. Daubeney PE , Pal K , Stanhope R . Hypomelanosis of Ito and precocious puberty . Eur J Pediatr . 1993;152:715–716
  13. Antoniazzi F , Zamboni G . Central precocious puberty (Current treatment options) . Paediatr Drugs . 2004;6:211–231

PII: S0887-8994(05)00285-7

doi: 10.1016/j.pediatrneurol.2005.06.004

Pediatric Neurology
Volume 34, Issue 1 , Pages 51-54 , January 2006

Article Tools

* Image Usage & Resolution