Levetiracetam in a Neonate With Malignant Migrating Partial Seizures
Received 11 January 2005; accepted 20 June 2005.
This report describes the first neonatal case of “malignant migrating partial seizures in infancy” with a positive therapeutic response to levetiracetam. This patient is the youngest reported infant with this rare syndrome, and the report provides the first documentation on levetiracetam treatment in a neonatal patient. Treatment with levetiracetam improved both ictal and interictal status. This observation also highlights the need to consider and include malignant migrating partial seizures in the differential diagnosis of early neonatal seizure disorders, even during the first hours of life.
⁎Neurologie Pédiatrique, Cliniques Universitaires Saint Luc (UCL), Brussels, Belgium