Pediatric Neurology
Volume 38, Issue 3 , Pages 181-185 , March 2008

Oxidative Stress in Perinatal Asphyxia

  • Ashok Kumar, MD

      Affiliations

    • Division of Neonatology, Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    • Corresponding Author InformationCommunications should be addressed to: Dr. Kumar; Division of Neonatology, Department of Pediatrics; Institute of Medical Sciences, Banaras Hindu University; Varanasi 221005, India.
    • ,
  • Satya Venkata Kalyan Ramakrishna, MD

      Affiliations

    • Division of Neonatology, Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    • ,
  • Sriparna Basu, MD

      Affiliations

    • Division of Neonatology, Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
    • ,
  • Gatram Rama Koteshwara Rao, PhD

      Affiliations

    • Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Received 10 May 2007 ,Accepted 8 October 2007.

References 

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  2. Harris ED. Regulation of antioxidant enzymes. FASEB J. 1992;6:2675–2683
  3. Singh SK, Dua T, Tandon A, Kumari S, Ray G, Batra S. Status of lipid peroxidation and anti-oxidant enzymes in hypoxic ischemic encephalopathy. Indian Pediatr. 1999;36:561–566
  4. Masotti L, Casali E, Galeotti T. Lipid peroxidation in tumor cells. Free Radic Biol Med. 1988;4:377–432
  5. Cheeseman KH, Slater TF. An introduction to free radical biochemistry. Br Med Bull. 1993;49:481–493
  6. Sies H. Oxidative stress: From basic research to clinical application. Am J Med. 1991;91(Suppl. 3C):31–39
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  9. Ellis M, Manandhar N, Manandhar DS, del Costello AM. An Apgar store of three or less at one minute is not diagnostic of birth asphyxia but is a useful screening test for neonatal encephalopathy. Indian Pediatr. 1998;35:415–421
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  11. Ellis M, Costello A. Birth asphyxia, Apgar score and neonatal encephalopathy. Indian Pediatr. 1997;34:975–978
  12. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med. 1967;70:158–169
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  14. Sinhuber RO, Yu TC. Characterization of red pigment formed in the Z-thiobarbituric acid determination of oxidative rancidity. Food Res. 1958;23:626–633
  15. Pitkanen OM, Hallman M, Andersson SM. Correlation of free oxygen radical-induced lipid peroxidation with outcome in very low birth weight infants. J Pediatr. 1990;116:760–764
  16. Frank L, Sosenko IRS. Development of lung antioxidant enzyme system in late gestation: Possible implications for the prematurely born infant. J Pediatr. 1987;110:9–14
  17. McCord JM. Oxygen derived free radicals in the post-ischemic tissue injury. N Engl J Med. 1985;312:159–163
  18. Kukreja RC, Kontos HA, Hess ML, Ellis EF. PGH synthetase and lipooxygenase generate superoxixe in the presence of NADH or NADPH. Circ Res. 1986;59:612–619
  19. Gutteridge JMC, Rowley DA, Haliwell B. Superoxide dependent formation of hydroxyl radicals in the presence of iron salts. Biochem J. 1981;199:263–265
  20. Kontos HA, Wel EP. Superoxide production in experimental brain injury. J Neurosurg. 1986;64:803–807
  21. Schmidt H, Grune T, Muller R, Siems WG, Wauer RR. Increased levels of lipid peroxidation products malondialdehyde and 4-hydroxynonenal after perinatal hypoxia. Pediatr Res. 1996;40:15–20
  22. Blum J, Fridovich I. Inactivation of glutathione peroxidase by superoxide radicals. Arch Biochem Biophys. 1985;240:500–508

PII: S0887-8994(07)00525-5

doi: 10.1016/j.pediatrneurol.2007.10.008

Pediatric Neurology
Volume 38, Issue 3 , Pages 181-185 , March 2008

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