Pediatric Neurology
Volume 41, Issue 5 , Pages 332-338 , November 2009

Medication Policy After Epilepsy Surgery

  • Kim Boshuisen, MD

      Affiliations

    • Department of Child Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
  • ,
  • Olga Braams, MSc

      Affiliations

    • Department of Pediatric Psychology, Neuropsychology Section, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    • Bio-Research and Treatment Centre Arnhem, Arnhem, The Netherlands
  • ,
  • Aag Jennekens-Schinkel, PhD

      Affiliations

    • Department of Pediatric Psychology, Neuropsychology Section, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    • Bio-Research and Treatment Centre Arnhem, Arnhem, The Netherlands
  • ,
  • Kees P. Braun, MD, PhD

      Affiliations

    • Department of Child Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
  • ,
  • Floor E. Jansen, MD, PhD

      Affiliations

    • Department of Child Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
  • ,
  • Peter C. van Rijen, MD, PhD

      Affiliations

    • Department of Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
  • ,
  • Onno van Nieuwenhuizen, MD, PhD

      Affiliations

    • Department of Child Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    • Corresponding Author InformationCommunications should be addressed to: Dr. van Nieuwenhuizen; Department of Child Neurology; University Medical Center; PO Box 85500; 3508 GA Utrecht; The Netherlands.

Received 27 October 2008 ,Accepted 27 April 2009.

References 

  1. Lachhwani DK, Loddenkemper T, Holland KD, et al. Discontinuation of medications after successful epilepsy surgery in children. Pediatric Neurol. 2008;38:340–344
  2. Van Oijen M, De Waal H, Van Rijen PC, Jennekens-Schinkel A, van Huffelen AC, Van Nieuwenhuizen O. Dutch Collaborative Epilepsy Surgery Program. Resective epilepsy surgery in childhood: the Dutch experience 1992-2002. Eur J Paediatr Neurol. 2006;10:114–123
  3. Polkey CE. Clinical outcome of epilepsy surgery. Curr Opin Neurol. 2004;17:173–178
  4. Sinclair DB, Aronyk KE, Snyder TJ, et al. Pediatric epilepsy surgery at the University of Alberta: 1988-2000. Pediatric Neurol. 2003;29:302–311
  5. Schmidt D, Baumgartner C, Löscher W. Seizure recurrence after planned discontinuation of antiepileptic drugs in seizure-free patients after epilepsy surgery: a review of current clinical experience. Epilepsia. 2004;45:179–186
  6. Kim YD, Heo K, Park SC, et al. Antiepileptic drug withdrawal after successful surgery for intractable temporal lobe epilepsy. Epilepsia. 2005;46:251–257
  7. Hoppe C, Poepel A, Sassen R, Elger CE. Discontinuation of anticonvulsant medication after epilepsy surgery in children. Epilepsia. 2006;47:580–583
  8. Sinclair DB, Jurasek L, Wheatley M, et al. Discontinuation of antiepileptic drugs after pediatric epilepsy surgery. Pediatric Neurol. 2007;37:200–202
  9. Krsek P, Maton B, Jayakar P, et al. Incomplete resection of focal cortical dysplasia is the main predictor of poor postsurgical outcome. Neurology. 2009;72:217–223
  10. Engel J. Update on surgical treatment of the epilepsies: summary of the Second International Palm Desert Conference on the Surgical Treatment of the Epilepsies (1992). Neurology. 1993;43:1612–1617
  11. Shinnar S, Berg AT, Moshé SL, et al. Discontinuing antiepileptic drugs in children with epilepsy: a prospective study. Ann Neurol. 1994;35:534–545
  12. Kim DW, Lee SK, Chu K, et al. Predictors of surgical outcome and pathologic considerations in focal cortical dysplasia. Neurology. 2009;72:211–216

PII: S0887-8994(09)00269-0

doi: 10.1016/j.pediatrneurol.2009.04.025

Pediatric Neurology
Volume 41, Issue 5 , Pages 332-338 , November 2009