Pediatric Neurology
Volume 41, Issue 5 , Pages 327-331 , November 2009

Seizures Are Common in Term Infants Undergoing Head Cooling

Received 21 January 2009 ,Accepted 4 May 2009.

References 

  1. Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: Multicentre randomized trial. Lancet. 2005;365:663–670
  2. Shankaran S, Laptook AR, Ehrenkranz RA, et al. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med. 2005;353:1574–1584
  3. Eicher DJ, Wagner CL, Katikaneni LP. Moderate hypothermia in neonatal encephalopathy: Efficacy outcomes. Pediatr Neurol. 2005;32:11–17
  4. Shah PS, Ohlsson A, Perlman M. Hypothermia to treat neonatal hypoxic ischemic encephalopathy: Systematic review. Arch Pediatr Adolesc Med. 2007;161:951–958
  5. Perlman M, Shah P. Time to adopt cooling for neonatal hypoxic-ischemic encephalopathy. Pediatrics. 2008;121:616–617
  6. Schulzke SM, Rao S, Patole SK. A systematic review of cooling for neuroprotection in neonates with hypoxic ischemic encephalopathy: Are we there yet?. BMC Pediatr. 2007;7:30
  7. Jacobs S, Hunt R, Tarnow-Mordi W, Inder T, Davis P. Cooling for newborns with hypoxic ischemic encephalopathy. Cochrane Database Syst Rev. 2007;4:CD003311
  8. Gunn AJ, Hoehn T, Hansmann G, et al. Hypothermia: An evolving treatment for neonatal hypoxic ischemic encephalopathy. Pediatrics. 2008;121:648–649
  9. Blackmon LR, Stark AR. Hypothermia: A neuroprotective therapy for neonatal hypoxic-ischemic encephalopathy. Pediatrics. 2006;11:942–948
  10. Higgins RD, Raju TN, Perlman J, et al. Hypothermia and perinatal asphyxia: Executive summary of the National Institute of Child Health and Human Development Workshop. J Pediatr. 2006;148:170–175
  11. Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch. Neurol. 1976;33:696–705
  12. Hagmann CF, Robertson NJ, Azzopardi D. Artifacts on electroencephalograms may influence the amplitude-integrated EEG classification: A qualitative analysis in neonatal encephalopathy. Pediatrics. 2006;118:2552–2554
  13. de Vries NKS, ter Horst HJ, Bos AF. The added value of simultaneous EEG and amplitude-integrated EEG recordings in three newborn infants. Neonatology. 2007;91:212–216
  14. al Naqeeb N, Edwards AD, Cowan FM, Azzopardi D. Assessment of neonatal encephalopathy by amplitude-integrated electroencephalography. Pediatrics. 1999;103:1263–1271
  15. Volpe JJ. Neurology of the newborn. 4th ed.. Philadelphia: W.B. Saunders; 2001;178-213
  16. Behrman RE, Kliegman RM, Jenson HB. Nelson textbook of pediatrics. 2nd ed.. Philadelphia: Saunders; 2004;2409-10
  17. Biagioni E, Mercuri E, Rutherford M, et al. Combined use of electroencephalogram and magnetic resonance imaging in full-term infants with acute encephalopathy. Pediatrics. 2001;107:461–468
  18. Sarker S, Barks JD, Donn SM. Should amplitude-integrated electroencephalography be used to identify infants suitable for hypothermic neuroprotection?. J Perinatol. 2008;28:117–122
  19. Shelhaas RA, Soiata A, Clancy RR. Sensitivity of amplitude-integrated electroencephalography for neonatal seizure detection. Pediatrics. 2007;120:770–777
  20. Wirrell EC. Neonatal seizures: To treat or not to treat. Semin Pediatr Neurol. 2005;12:97–105
  21. Dzhala V, Ben-Ari Y, Khazipov R. Seizures accelerate anoxia-induced neuronal death in the neonatal rat hippocampus. Ann Neurol. 2000;48:632–640
  22. Holmes GL, Gairsa JL, Chevassus AUL, Ben-Ari Y. Consequences of neonatal seizures in the rat: Morphological and behavioral effects. Ann Neurol. 1998;44:845–857
  23. Silverstein FS, Jensen FE. Neonatal seizures. Ann Neurol. 2007;62:112–120
  24. McBride MC, Laroia N, Guillet R. Electrographic seizures in neonates correlate with poor neurodevelopmental outcome. Neurology. 2000;55:506–514
  25. Legido A, Clancy RR, Berman PH. Neurological outcome after electroencephalographically proven neonatal seizures. Pediatrics. 1991;88:583–596
  26. Miller SP, Weiss J, Barnwell A, et al. Seizure-associated brain injury in term newborns with perinatal asphyxia. Neurology. 2002;58:542–548
  27. Hall RT, Hall FK, Daily DK. High dose phenobarbital in term newborns with perinatal asphyxia: A randomized prospective study with three year follow-up with three year follow-up. J Pediatr. 1998;132:345–348
  28. Marret S, Gressens P, Gadisseux JF, Evrard P. Prevention by magnesium of excitotoxic neuronal death in the developing brain: An animal model of clinical intervention studies. Dev Med Child Neurol. 1995;37:473–484
  29. Penrice J, Amess PN, Punwani S, et al. Magnesium sulfate after transient hypoxia-ischemia fails to prevent delayed cerebral energy failure in the newborn piglet. Pediatr Res. 1997;41:443–447
  30. de Haan HH, Gunn AJ, Williams CE, Heymann MA, Gluckman PD. Magnesium sulfate therapy during asphyxia in near-term fetal lambs does not compromise the fetus but does not reduce cerebral injury. Am J Obstet Gynecol. 1997;176:18–27
  31. Nelson KB, Grether JK. Can magnesium sulfate reduce the risk of cerebral palsy in very low birthweight infants?. Pediatrics. 1997;95:263–269
  32. Ischiba H. Randomized controlled trial of magnesium sulfate infusion for severe birth asphyxia. Pediatr Int. 2002;44:505–509

PII: S0887-8994(09)00271-9

doi: 10.1016/j.pediatrneurol.2009.05.004

Pediatric Neurology
Volume 41, Issue 5 , Pages 327-331 , November 2009

Article Tools