Pediatric Neurology
Volume 41, Issue 6 , Pages 445-447 , December 2009

Giant Cystic Lesion in Neurofibromatosis

  • Rony Cohen, MD

      Affiliations

    • Department of Pediatric Neurology and Epilepsy Center, Petach-Tikva, Israel
    • Corresponding Author InformationCommunications should be addressed to: Dr. Cohen; Department of Pediatric Neurology and Epilepsy Center; Schneider Children's Medical Center; 14 Kaplan Street; Petach-Tikva 49202, Israel.
  • ,
  • Liora Kornreich, MD

      Affiliations

    • Department of Pediatric Radiology, Schneider Children's Medical Center, Petach-Tikva, Israel
  • ,
  • Avinoam Shuper, MD

      Affiliations

    • Department of Pediatric Neurology and Epilepsy Center, Petach-Tikva, Israel

Received 18 February 2009 ,Accepted 30 June 2009.

References 

  1. Rott H-D, Lemcke B, Zenker M, Huk W, Horst J, Mayer K. Cyst-like cerebral lesions in tuberous sclerosis. Am J Med Genet. 2002;111:435–439
  2. Jurkiewicz E, Jozwiak S, Bekiesinska-Figatowska M, Pakula-Kosciesza Walecki J. Cyst-like cortical tubers in patients with tuberous sclerosis complex: MR imaging with the FLAIR sequence. Pediatr Radiol. 2006;36:498–501
  3. Rosman NP, Pearce J. The brain in multiple neurofibromatosis (von Recklinghausen's disease): a suggested neuropathological basis for the associated mental defect. Brain. 1967;14:829–838
  4. Cusmai R, Curatolo P, Mangano S, Cheminal R, Echenne B. Hemimegalencephaly and neurofibromatosis. Neuropediatrics. 1990;21:179–182
  5. Balestri P, Vivarelli R, Santori L, et al. Malformation of cortical development in neurofibromatosis type 1. Neurology. 2003;61:1799–1801
  6. Hegedus B, Dasgupta B, Shin JE, et al. Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms. Cell Stem Cell. 2007;1:443–457
  7. Lush ME, Li Y, Kwon CH, Chen J, Parada LF. Neurofibromin is required for barrel formation in the mouse somatosensory cortex. J Neurosci. 2008;28:1580–1587
  8. Adachi M, Hosoya T, Haku T, Yamaguchi K. Dilated Virchow-Robin spaces: MRI pathological study. Neuroradiology. 1998;40:27–31
  9. Groeschel S, Chong WK, Surtees R, Hanefeld F. Virchow-Robin spaces on magnetic resonance images: normative data, their dilatation, and a review of the literature. Neuroradiology. 2006;48:745–754
  10. Ogawa T, Okudera T, Fukasawa H, et al. Unusual widening of Virchow-Robin spaces: MR appearance. AJNR Am J Neuroradiol. 1995;16:1238–1242
  11. Shiratori K, Mrowka M, Toussaint A, Spalke G, Bien S. Extreme, unilateral widening of Virchow-Robin spaces: case report. Neuroradiology. 2002;44:990–992
  12. Mathias J, Koessler L, Brissart H, et al. Giant cystic widening of Virchow-Robin spaces: an anatomofunctional study. AJNR Am J Neuroradiol. 2007;28:1523–1525
  13. Heier LA, Bauer CJ, Schwartz L, Zimmerman RD, Morgello S, Deck MD. Large Virchow-Robin spaces: MR-clinical correlation. AJNR Am J Neuroradiol. 1989;10:929–936
  14. Kwee RM, Kwee TC. Virchow-Robin spaces at MR Imaging. Radiographics. 2007;27:1071–1086
  15. Artigas J, Poo P, Rovira A, Cardo E. Macrocephaly and dilated Virchow-Robin spaces in childhood. Pediatr Radiol. 1999;29:188–190
  16. Rollins NK, Deline C, Morriss MC. Prevalence and clinical significance of dilated Virchow-Robin spaces in childhood. Radiology. 1993;189:53–57
  17. Park MS, Suh DC, Choi WS, Lee SY, Kang GH. Multifocal meningioangiomatosis: a report of two cases. AJNR Am Neuroradiol. 1999;20:677–680
  18. Hohman DW, Noghrehkar D, Ratnayake S. Lymphangioleiomyomatosis: a review. Eur J Intern Med. 2008;19:319–324
  19. Grosso S, Cerase A, De Stefano N, et al. Non-progressive leukoencephalopathy with bilateral anterior temporal cyst: a case report and review of the literature. Brain Dev. 2005;27:73–77
  20. Cho SB, Kim HS, Yang MS, Cho KW. Type 1 neurofibromatosis associated with asymptomatic cystic malformations of central nervous system (CNS). Int J Dermatol. 2009;48:330–332

PII: S0887-8994(09)00354-3

doi: 10.1016/j.pediatrneurol.2009.06.009

Pediatric Neurology
Volume 41, Issue 6 , Pages 445-447 , December 2009