Pediatric Neurology
Volume 41, Issue 6 , Pages 461-463 , December 2009

Vincristine-Induced Unilateral Ptosis in a Child

  • Orhan Gursel, MD

      Affiliations

    • Department of Pediatric Hematology, Gulhane Military Medical Academy and Medical Faculty, Ankara, Turkey
    • Corresponding Author InformationCommunications should be addressed to: Dr. Gürsel; Department of Pediatric Hematology; Gulhane Military Medical Academy and Medical Faculty; 06018 Etlik; Ankara, Turkey.
    • ,
  • Erkan Sari, MD

      Affiliations

    • Department of Pediatrics, Gulhane Military Medical Academy and Medical Faculty, Ankara, Turkey
    • ,
  • Demet Altun, MD

      Affiliations

    • Department of Pediatrics, Gulhane Military Medical Academy and Medical Faculty, Ankara, Turkey
    • ,
  • A. Avni Atay, MD

      Affiliations

    • Department of Pediatric Hematology, Gulhane Military Medical Academy and Medical Faculty, Ankara, Turkey
    • ,
  • Ridvan Akin, MD

      Affiliations

    • Department of Pediatric Neurology, Gulhane Military Medical Academy and Medical Faculty, Ankara, Turkey

Received 22 April 2009 ,Accepted 6 July 2009.

References 

  1. Rowinsky EK, Donehower RC. Systemic chemotherapy. In:  Perry MC editors. The chemotherapy source book. 2nd ed. Baltimore: Williams & Wilkins; 1996;p. 116–140
  2. Albert DM, Wong VG, Henderson ES. Ocular complications of vincristine therapy. Arch Ophthalmol. 1967;78:709–713
  3. Parentin F, Liberali T, Perissutti P, Rabusin M. Unilateral palpebral ptosis associated with vinblastine therapy. Neuroophthalmology. 2005;29:133–135
  4. Müller L, Kramm CM, Tenenbaum T, Wessalowski R, Göbel U. Treatment of vincristine-induced bilateral ptosis with pyridoxine and pyridostigmine. Pediatr Blood Cancer. 2004;42:287–288
  5. Bay A, Yilmaz C, Yilmaz N, Oner AF. Vincristine induced cranial polyneuropathy. Indian J Pediatr. 2006;73:531–533
  6. Legha SS. Vincristine neurotoxicity: pathophysiology and management. Med Toxico1. 1986;1:421–427
  7. Wang WS, Chiou TJ, Liu JH, Fan FS, Yen CC, Chen PM. Vincristine induced dysphagia suggesting esophageal motor dysfunction: a case report. Jpn J Clin Oncol. 2000;30:515–518
  8. Sandler SG, Tobin W, Henderson ES. Vincristine-induced neuropathy: a clinical study of fifty leukemic patients. Neurology. 1969;19:367–374
  9. Quasthoff S, Hartung HP. Chemotherapy-induced peripheral neuropathy. J Neurol. 2002;249:9–17
  10. Jackson DV, Pope EK, McMahan RA, et al. Clinical trial of pyridoxine to reduce vincristine neurotoxicity. J Neurooncol. 1986;4:37–41

PII: S0887-8994(09)00355-5

doi: 10.1016/j.pediatrneurol.2009.07.005

Pediatric Neurology
Volume 41, Issue 6 , Pages 461-463 , December 2009

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