Pediatric Neurology
Volume 41, Issue 6 , Pages 457-460 , December 2009

Secondary Tics or Tourettism Associated With a Brain Tumor

  • Aimee F. Luat, MD

      Affiliations

    • Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
    • Department of Neurology, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
    • ,
  • Michael E. Behen, PhD

      Affiliations

    • Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
    • Department of Neurology, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
    • ,
  • Csaba Juhász, MD, PhD

      Affiliations

    • Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
    • Department of Neurology, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
    • ,
  • Sandeep Sood, MD

      Affiliations

    • Department of Neurosurgery, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
    • ,
  • Harry T. Chugani, MD

      Affiliations

    • Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
    • Department of Neurology, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
    • Department of Radiology, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan
    • Corresponding Author InformationCommunications should be addressed to: Dr. Chugani; Pediatric Neurology/PET Center; Children's Hospital of Michigan; 3901 Beaubien Blvd.; Detroit, MI 48201.

Received 21 January 2009 ,Accepted 13 July 2009.

References 

  1. Jankovic J. Tourette syndrome. N Engl J Med. 2001;345:1184–1192
  2. Mejia NI, Jankovic J. Secondary tics and tourettism. Rev Bras Psiquiatr. 2005;27:11–17
  3. Singer HS. Tourette's syndrome: from behaviour to biology. Lancet Neurol. 2005;4:149–159
  4. Behen M, Chugani HT, Juhász C, et al. Abnormal brain tryptophan metabolism and clinical correlates in Tourette syndrome. Mov Disord. 2007;22:2256–2262
  5. American Psychiatric Association. Task Force on DSM-IV. Diagnostic and statistical manual of mental disorders: DSM-IV-TR. 4th ed., text revision. Washington, DC: American Psychiatric Association; 2000;
  6. Roessner V, Robatzek M, Knapp G, Banaschewski T, Rothenberger A. First-onset tics in patients with attention-deficit-hyperactivity disorder: impact of stimulants. Dev Med Child Neurol. 2006;48:616–621
  7. Singer HS, Minzer K. Neurobiology of Tourette's syndrome: concept of neuroanatomic localization and neurochemical abnormalities. Brain Dev. 2003;25(Suppl. 1):S70–S84
  8. Peterson BS, Thomas P, Kane MJ, et al. Basal ganglia volumes in patients with Gilles de La Tourette syndrome. Arch Gen Psychiatry. 2003;60:415–424
  9. Makki MI, Behen M, Bhatt A, Wilson B, Chugani HT. Microstructural abnormalities of striatum and thalamus in children with Tourette syndrome. Mov Disord. 2008;23:2349–2356
  10. Makki MI, Govindan RM, Wilson BJ, Behen ME, Chugani HT. Altered fronto-striato-thalamic connectivity in children with Tourette syndrome assessed with diffusion tensor MRI and probabilistic fiber tracking. J Child Neurol. 2009;24:669–678
  11. Braun AR, Stoetter B, Randolph C, et al. The functional neuroanatomy of Tourette's syndrome: an FDG-PET study. I. Regional changes in cerebral glucose metabolism differentiating patients and controls. Neuropsychopharmacology. 1993;9:277–291
  12. Braun AR, Randolph C, Stoetter B, et al. The functional neuroanatomy of Tourette's syndrome: an FDG-PET study. II. Relationships between regional cerebral metabolism and associated behavioral and cognitive features of the illness. Neuropsychopharmacology. 1995;13:151–168
  13. Yoon DY, Gause CD, Leckman JF, Singer HS. Frontal dopaminergic abnormality in Tourette syndrome: a postmortem analysis. J Neurol Sci. 2007;255:50–56
  14. Comings DE. Blood serotonin and tryptophan in Tourette syndrome. Am J Med Genet. 1990;36:418–430
  15. Leckman JF, Goodman WK, Anderson GM, et al. Cerebrospinal fluid biogenic amines in obsessive compulsive disorder, Tourette's syndrome, and healthy controls. Neuropsychopharmacology. 1995;12:73–86
  16. Heinz A, Knable MB, Wolf SS, et al. Tourette's syndrome: [I-123]β-CIT SPECT correlates of vocal tic severity. Neurology. 1998;51:1069–1074
  17. Juhász C, Chugani DC, Muzik O, et al. In vivo uptake and metabolism of α-[11C]methyl-L-tryptophan in human brain tumors. J Cereb Blood Flow Metab. 2006;26:345–357

PII: S0887-8994(09)00359-2

doi: 10.1016/j.pediatrneurol.2009.07.009

Pediatric Neurology
Volume 41, Issue 6 , Pages 457-460 , December 2009

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