Pediatric Neurology
Volume 42, Issue 3 , Pages 213-214 , March 2010

Anti-N-Methyl-d-Aspartate Receptor Encephalitis: Early Treatment is Beneficial

  • Erin H. Breese, MD, PhD

      Affiliations

    • Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana
    • ,
  • Joseph Dalmau, MD, PhD

      Affiliations

    • Division of Neuro-oncology, Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania
    • ,
  • Vanda A. Lennon, MD, PhD

      Affiliations

    • Departments of Neurology, Immunology, and Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Metha Apiwattanakul, MD

      Affiliations

    • Departments of Neurology, Immunology, and Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Deborah K. Sokol, PhD, MD

      Affiliations

    • Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana
    • Corresponding Author InformationCommunications should be addressed to: Dr. Sokol; Riley Hospital for Children; Department of Neurology XE40; Indiana University School of Medicine; 575 West Drive; Indianapolis, IN, 46202.

Received 20 July 2009 ,Accepted 12 October 2009.

References 

  1. Dalmau J, Gleichman AJ, Hughes EG, et al. Anti-NMDA receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol. 2008;7:1091–1098
  2. Dalmau J, Tuzun E, Wu HY, et al. Paraneoplastic anti- N-methyl-d-aspartate receptor encephalitis associated with ovarian teratoma. Ann Neurol. 2007;61:25–36
  3. Vitaliani R, Mason W, Ances B, Zwerdling T, Jiang Z, Dalmau J. Paraneoplastic encephalitis, psychiatric symptoms, and hypoventilation in ovarian teratoma. Ann Neurol. 2005;58:594–604
  4. Iizuka T, Sakai F, Ide T, et al. Anti-NMDA receptor encephalitis in Japan: long-term outcome without tumor removal. Neurology. 2008;70:504–511
  5. Ishiura H, Matsuda S, Higashihara M, et al. Response of anti-NMDA receptor encephalitis without tumor to immunotherapy including rituximab. Neurology. 2008;71:1921–1923

PII: S0887-8994(09)00484-6

doi: 10.1016/j.pediatrneurol.2009.10.003

Pediatric Neurology
Volume 42, Issue 3 , Pages 213-214 , March 2010

Article Tools