Pediatric Neurology
Volume 43, Issue 1 , Pages 49-52 , July 2010

Epilepsy: An Anticipatory Presentation of Pediatric Wegener's Granulomatosis

  • Brooke M. Moore, MD, MPH

      Affiliations

    • Department of Pediatrics, University of Minnesota School of Medicine and Amplatz Children's Hospital, Minneapolis, Minnesota
    • Division of Pediatric Pulmonology, University of Minnesota School of Medicine, Minneapolis, Minnesota
    • Corresponding Author InformationCommunications should be addressed to: Dr. Moore; Department of Pediatrics, University of Minnesota School of Medicine; 420 Delaware Street Southeast; Minneapolis, MN 55455.
    • ,
  • Steven M. Rothman, MD

      Affiliations

    • Department of Pediatrics, University of Minnesota School of Medicine and Amplatz Children's Hospital, Minneapolis, Minnesota
    • Division of Pediatric Neurology, University of Minnesota School of Medicine, Minneapolis, Minnesota
    • ,
  • H. Brent Clark, MD, PhD

      Affiliations

    • Department of Laboratory Medicine and Pathology, University of Minnesota School of Medicine, Minneapolis, Minnesota
    • ,
  • Richard K. Vehe, MD

      Affiliations

    • Department of Pediatrics, University of Minnesota School of Medicine and Amplatz Children's Hospital, Minneapolis, Minnesota
    • Division of Pediatric Rheumatology, University of Minnesota School of Medicine, Minneapolis, Minnesota
    • ,
  • Theresa A. Laguna, MD, MSCS

      Affiliations

    • Department of Pediatrics, University of Minnesota School of Medicine and Amplatz Children's Hospital, Minneapolis, Minnesota
    • Division of Pediatric Pulmonology, University of Minnesota School of Medicine, Minneapolis, Minnesota

Received 22 October 2009 ,Accepted 15 March 2010.

References 

  1. Leavitt RY, Fauci AS, Bloch DA, et al. The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis. Arthritis Rheum. 1990;33:1101–1107
  2. Drachman DD. Neurological complications of Wegener's granulomatosis. Arch Neurol. 1963;8:145–155
  3. Nishino H, Rubino FA, DeRemee RA, Swanson JW, Parisi JE. Neurological involvement in Wegener's granulomatosis: An analysis of 324 consecutive patients at the Mayo Clinic. Ann Neurol. 1993;33:4–9
  4. Hoffman GS, Kerr GS, Leavitt RY, et al. Wegener granulomatosis: An analysis of 158 patients. Ann Intern Med. 1992;116:488–498
  5. Haas JP, Metzler M, Ruder H, Waldherr R, Boswald M, Rupprecht T. An unusual manifestation of Wegener's granulomatosis in a 4-year-old girl. Pediatr Neurol. 2002;27:71–74
  6. Taylor CT, Buring SM, Taylor KH. Treatment of Wegener's granulomatosis with immune globulin: CNS involvement in an adolescent female. Ann Pharmacother. 1999;33:1055–1059
  7. Ulinski T, Martin H, MacGregor B, Dardelin R, Cochat P. Fatal neurologic involvement in pediatric Wegener's granulomatosis. Pediatr Neurol. 2005;32:278–281
  8. von Scheven E, Lee C, Berg BO. Pediatric Wegener's granulomatosis complicated by central nervous system vasculitis. Pediatr Neurol. 1998;19:317–319
  9. de Groot K, Schmidt DK, Arlt AC, Gross WL, Reinhold-Keller E. Standardized neurologic evaluations of 128 patients with Wegener granulomatosis. Arch Neurol. 2001;58:1215–1221
  10. Miller KS, Miller JM. Wegener's granulomatosis presenting as a primary seizure disorder with brain lesions demonstrated by magnetic resonance imaging. Chest. 1993;103:316–318
  11. Provenzale JM, Allen NB. Wegener granulomatosis: CT and MR findings. AJNR. 1996;17:785–792
  12. Murphy JM, Gomez-Anson B, Gillard JH, et al. Wegener's granulomatosis: MR imaging findings in brain and meninges. Radiology. 1999;213:794–799
  13. Rao JK, Weinberger M, Oddone EZ, Allen NB, Landsman P, Feussner JR. The role of antineutrophil cytoplasmic antibody (c-ANCA) testing in the diagnosis of Wegener granulomatosis. A literature review and meta-analysis. Ann Intern Med. 1995;123:925–932
  14. Weinberger LM, Cohen ML, Remler BF, Naheedy MH, Leigh RJ. Intracranial Wegener's granulomatosis. Neurology. 1993;43:1831–1834

PII: S0887-8994(10)00146-3

doi: 10.1016/j.pediatrneurol.2010.03.014

Pediatric Neurology
Volume 43, Issue 1 , Pages 49-52 , July 2010

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