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Communications should be addressed to: Dr. Taraschenko; Department of Neurology; Emory University; 101 Woodruff Circle, Suite 6000; Atlanta, Georgia 30322.
A 23-day-old girl with a history of transposition of the great arteries, ventricular
septal defect, pulmonary stenosis, and placement of right modified Blalock-Taussig
shunt complicated by thrombosis at age 9 days of life presented with episodes of upper
extremity extension and gasping respirations concerning for seizure. Brain magnetic
resonance imaging demonstrated an extensive, acute right middle carotid artery territory
stroke with occlusion of the right proximal middle carotid artery. There was also
a small left frontal stroke. Diffusion restriction abnormalities with simultaneous
presence of hyperintensity on T2 sequences in the corticospinal tract consistent with early Wallerian degeneration
were observed (Figure).
FigureInitial brain magnetic resonance imaging at 22 days of age revealed diffusion restriction
abnormalities in the right middle carotid artery territory (A). Wallerian degeneration
within the right corticospinal tract at the level of internal capsule (A), midbrain
(B), rostral pons (C), and caudal pons (D) is depicted by the arrow.
Correlation between neonatal cranial ultrasound, MRI in infancy and neurodevelopmental outcome in infants with a large intraventricular haemorrhage with or without unilateral parenchymal involvement.
O.T. was responsible for drafting/revising the article, study concept, and analysis of data. C.N. was responsible for drafting/revising the article, study design, analysis and acquisition of data. J.P. was responsible for drafting/revising the article, analysis and acquisition of data, and study supervision.
