The past two decades have seen a remarkable increase in publications on pediatric
stroke, reflecting increased awareness of its impact on childhood health. The results
of the Stroke Prevention Trial in Sickle Cell Anemia (STOP), published in 1998, which
showed that chronic blood transfusion decreased the risk of stroke in high-risk children
with sickle cell anemia by 92%, revolutionized the care of children with sickle cell
anemia
1
and highlighted the importance of primary stroke prevention. Surgical revascularization
is used increasingly to decrease the risk of ischemic and hemorrhagic stroke in children
with moyamoya cerebral arteriopathy.
2
Consensus-based guidelines now exist to guide the care of children with stroke, and
prevent stroke recurrence,
3
,
4
while consensus-based standards are being established for pediatric stroke centers
of excellence.
5
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References
- Stroke prevention trial in sickle cell anemia.Control Clin Trials. 1998; 19: 110-129
- Spontaneous occlusion of the circle of Willis in children: pediatric moyamoya summary with proposed evidence-based practice guidelines. A review.J Neurosurg Pediatr. 2012; 9: 353-360
- Management of stroke in infants and children: a scientific statement from a Special Writing Group of the American Heart Association Stroke Council and the Council on Cardiovascular Disease in the Young.Stroke. 2008; 39: 2644-2691
- Antithrombotic therapy in neonates and children: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.Chest. 2012; 141: e737S-e801S
- Emergence of the Primary Pediatric Stroke Center: Impact of the Thrombolysis in Pediatric Stroke Trial.Stroke. 2014; 45: 2018-2023
- The cost of pediatric stroke care and rehabilitation.Stroke. 2008; 39: 161-165
- Delays in investigation and management of acute arterial ischaemic stroke in children.Dev Med Child Neurol. 2008; 50: 537-540
- Delay to diagnosis in acute pediatric arterial ischemic stroke.Stroke. 2009; 40: 58-64
- Delayed recognition of initial stroke in children: need for increased awareness.Pediatrics. 2009; 124: e227-e234
- Mimics of childhood stroke: characteristics of a prospective cohort.Pediatrics. 2006; 118: 704-709
- Abstract 37: Pediatric brain attacks: differentiating between stroke and mimics in the emergency room.Stroke. 2014; 45: A37
- Thrombolysis in pediatric stroke study.Stroke. 2015; 46: 880-885
- Predictors of cerebral arteriopathy in children with arterial ischemic stroke: results of the International Pediatric Stroke Study.Circulation. 2009; 119: 1417-1423
- Risk of recurrent childhood arterial ischemic stroke in a population-based cohort: the importance of cerebrovascular imaging.Pediatrics. 2007; 119: 495-501
- Investigation of risk factors in children with arterial ischemic stroke.Ann Neurol. 2003; 53: 167-173
- Prospective assessment of risk factors for recurrent stroke during childhood – a 5-year follow-up study.Lancet. 2002; 360: 1540-1545
- Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.Stroke. 2013; 44: 870-947
- Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR).Stroke. 2009; 40: 2442-2449
- Thrombolysis for acute ischemic stroke: results of the Canadian Alteplase for Stroke Effectiveness Study.CMAJ. 2005; 172: 1307-1312
- Endovascular therapy after intravenous t-PA versus t-PA alone for stroke.N Engl J Med. 2013; 368: 893-903
- A randomized trial of intraarterial treatment for acute ischemic stroke.N Engl J Med. 2015; 372: 11-20
- Solitaire with the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME) trial: protocol for a randomized, controlled, multicenter study comparing the Solitaire revascularization device with IV tPA with IV tPA alone in acute ischemic stroke.Int J Stroke. 2015; 10: 439-448
- Endovascular therapy for ischemic stroke with perfusion-imaging selection.N Engl J Med. 2015; 372: 1009-1018
- Endovascular treatment for Small Core and Anterior circulation Proximal occlusion with Emphasis on minimizing CT to recanalization times (ESCAPE) trial: methodology.Int J Stroke. 2015; 10: 429-438
- Mechanical embolectomy for ischemic stroke in a pediatric ventricular assist device patient.Pediatr Transplant. 2014; 18: E88-E92
- Use of alteplase in childhood arterial ischaemic stroke: a multicentre, observational, cohort study.Lancet Neurol. 2009; 8: 530-536
- Failure of a clot retrieval device in an adolescent stroke patient.Pediatr Neurol. 2010; 43: 435-438
- Antithrombotic treatments, outcomes, and prognostic factors in acute childhood-onset arterial ischaemic stroke: a multicentre, observational, cohort study.Lancet Neurol. 2009; 8: 1120-1127
- Recommendations for the establishment of stroke systems of care: recommendations from the American Stroke Association's Task Force on the Development of Stroke Systems.Stroke. 2005; 36: 690-703
- Paediatric stroke: pressing issues and promising directions.Lancet Neurol. 2015; 14: 92-102
Article info
Publication history
Published online: December 09, 2015
Identification
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© 2016 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
