Neuroplasticity has gained notoriety as a term used to describe the brain's ability
to develop new connections following injury, with an implication for functional recovery.
From the neonatal brain to an adult stroke survivor, the central nervous system has
the remarkable ability to change through experience-dependent plasticity. But what
happens when those experiences are negative life experiences rather than positive?
Instead of a brain focused on stimulation and rehabilitation, what happens when the
developing nervous system is exposed to the neural, biochemical, and hormonal effects
of overwhelming stress such as neglect or chronic maltreatment?
Keywords
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References
- Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) study.Am J Prev Med. 1998; 14: 245-258
- A.E. Bennett research award. Developmental traumatology. Part II: brain development.Biol Psychiatry. 1999; 45: 1271-1284
- Post-traumatic stress disorder: the neurobiological impact of psychological trauma.Dialogues Clin Neurosci. 2011; 13: 263-278
- The effects of childhood maltreatment on brain structure, function and connectivity.Nat Rev Neurosci. 2016; 17: 652-666
- Sensory filtering phenomenology in PTSD.Depress Anxiety. 2008; 25: 38-45
- Neuroimaging of child abuse: a critical review.Front Hum Neurosci. 2012; 6: 52
- Cortical thickness alterations linked to somatoform and psychological dissociation in functional neurological disorders.Hum Brain Mapp. 2018; 39: 428-439
- Heart period and variability findings in preschool children with posttraumatic stress symptoms.Biol Psychiatry. 2004; 55: 685-691
- Autonomic dysregulation in panic disorder and in post-traumatic stress disorder: application of power spectrum analysis of heart rate variability at rest and in response to recollection of trauma or panic attacks.Psychiatry Res. 2000; 96: 1-13
- Childhood maltreatment and migraine (part I). Prevalence and adult revictimization: a multicenter headache clinic survey.Headache. 2010; 50: 20-31
Article info
Publication history
Published online: March 26, 2018
Accepted:
March 18,
2018
Received:
March 15,
2018
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.
